Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

Researchers create RNA molecules to address human pancreatic beta cells

Researchers at the University of Miami Miller School of Medicine have created RNA molecules that bind to human pancreatic beta cells, which generate insulin and are destroyed in type 1 and type 2 diabetes patients.

11 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

UTSA team develops innovative inhibitor to fight obesity and heart disease

An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.

4 Mar 2022

Study details metabolic processes employed by SARS-CoV-2 to attack lung tissue

Scientists from the Karolinska Institutet discovered certain metabolic mechanisms that SARS-CoV-2 employs to attack lung tissue.

13 Oct 2021

Study explores the link between antibiotics use, gut microbiota, and lifespan

A group of scientists have identified a connection between the type of microbiome that recolonizes the gut after antibiotics and the lessened lifespan in mice.

31 Aug 2021

Study analyzes the health benefits of time-restricted eating

Time-restricted eating (TRE) is a dietary regimen in which eating is restricted to particular hours. It has received great attention in weight-loss circles.

19 Aug 2021

Life expectancy can be increased by an average of 30% in transgenic mice, study shows

Aging is associated with an overall decline in health and increased frailty, and is a major risk factor for multiple chronic diseases.

2 Jun 2021

Processed diet reduces gut bacteria and promotes encroachment of microbiota into the intestine

Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Apr 2021

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

Consumption of a diet with high fat levels increases the risk of fatty liver, obesity, cardiovascular diseases, and type 2 diabetes.

15 Mar 2021

UMD awarded grant to explore nettle as a functional food for improving health

Obesity, diabetes, and overall immune system health are issues that are all top-of-mind right now, especially during the pandemic.

9 Mar 2021

New perspectives challenge diet-heart-hypothesis

In science, sometimes a new perspective can turn our interpretation of the data upside-down, and necessitate a paradigm shift.

25 Jan 2021

Periodontal or gum disease recognized as significant risk factor for metabolic syndrome

Researchers from Tokyo Medical and Dental University (TMDU) identify a novel mechanism by which periodontal disease may cause diabetes

11 Dec 2020

Study links air pollution and diabetes to interstitial lung disease

People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate.

10 Dec 2020

Understanding beta-cell growth mechanisms may help treat metabolic diseases

New treatments for metabolic diseases, such as type 2 diabetes, could emerge from a study of how a single enzyme controls the growth of the pancreatic cells that produce insulin.

5 Oct 2020

Identifying genetic factors that mitigate the risk of diabetes

A rice-based diet is a traditional food among certain east-Asian population and has ushered in several genomic adaptations that may play a role in obesity.

22 Sep 2020

Study shows how DUSP8 protein regulates glucose tolerance, insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

24 Aug 2020

Exposure to air pollution may increase risk of cardiometabolic diseases

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

21 Aug 2020

Increased fructose intake during pregnancy can alter offspring's metabolism

An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found.

19 Aug 2020