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Researchers fine-tune an additional system for more efficient gene editing

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone Institutes have fine-tuned an additional system for more efficient gene editing, using molecules called retrons.

6 Jan 2022

NRL scientists apply new methods to analyze cell behavior

Naval Research Laboratory researchers in the Chemistry Division apply their knowledge of biology in conjunction with materials to improve understanding of how cells and tissues organize and apply new methods to affect cell communication.

From United States Naval Research Laboratory 6 Jan 2022

Study illustrates the concept of cool microscopy

Fluorescence light microscopy has the unique ability to observe cellular processes over a scale that bridges four orders of magnitude. Yet, its application to living cells is fundamentally limited by the very rapid and unceasing movement of molecules that define its living state.

From The Max Planck Institute 14 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

Live-cell probes enable visualization of the elongation phase of transcription

A genetically encoded “live-cell” probe developed by scientists from Tokyo Tech pinpointed phosphorylated Ser2 in the enzyme RNA polymerase II.

7 Dec 2021

Creating a Biological Clock in a Test Tube

We speak to researchers from the UC San Diego Center for Circadian Biology about their latest research that led to the development of a biological clock in a test tube.

From UC San Diego 6 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

New technique for label-free identification of microplastics in human cells

The research is supported by the Russian Science Foundation (grant 21-73-00097).

23 Nov 2021

Study results facilitate construction of complex nanoscale computing agents

Scientists for the first time developed a nano computing agent that regulates the function of a specific protein involved in cell movement and cancer metastasis.

From Penn State University 19 Nov 2021

Formation of transcription factories in living cells resembles the condensation of liquids

It is essential for cells to control precisely which of the many genes of their genetic material they use. This is done in so-called transcription factories, molecular clusters in the nucleus.

5 Nov 2021

Researchers reveal how bacteria make liquid protein droplets to survive harsh environments

Scientists have revealed how bacteria make tiny liquid droplets from proteins to help them survive harsh environments and thus reduce their chances of being killed by antibiotics.

21 Oct 2021

Study investigates the role of essential genes in acetic acid tolerance

Saccharomyces cerevisiae, also known as Baker’s yeast, is industrially utilized for the production of different biochemicals.

21 Oct 2021

Novel technique shows molecule conformations in live cells

Comprehending how proteins twist, bend, and shape-shift, as they work in cells, is vital to gain insights into diseases and normal biology.

21 Oct 2021

Metabolic restoration could provide natural protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

19 Oct 2021

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

With advances in deep learning, machines are now able to "predict" a variety of aspects about life, including the way people interact on online platforms or the way they behave in physical environments.

15 Oct 2021

New smart microscope developed for the imaging of biological surfaces

Modern biology relies on our ability to observe living cells using microscopes. The latest advances in optical microscopy allow cellular and sub-cellular imaging within model organisms such as the vinegar fly, zebrafish or mouse.

13 Oct 2021

Researchers develop a novel sensor to detect chemical changes in immune cells

Three chemists from the Indiana University Bloomington developed a novel sensor to identify chemical changes in immune cells at the time of the pathogen breakdown.

13 Oct 2021

Researchers reconstitute the biological clock to better understand circadian rhythms

Daily cycles in virtually every aspect of our physiology are driven by biological clocks (also called circadian clocks) in our cells.

From University of California Santa Cruz 8 Oct 2021

Study offers important insights into how circadian clocks function at the subcellular level

Almost every living thing on Earth-;from bacteria to plants to people-;have a circadian rhythm, the biological clock that controls both physiology and behavior of organisms over a 24-hour period.

1 Oct 2021

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are known to influence every aspect of DNA activity, but how this happens has not been clear.

28 Sep 2021

Living Cells News and Research

Researchers fine-tune an additional system for more efficient gene editing

NRL scientists apply new methods to analyze cell behavior

Study illustrates the concept of cool microscopy

Powering the Biotechnology Revolution through Cloud R&D

Live-cell probes enable visualization of the elongation phase of transcription

Creating a Biological Clock in a Test Tube

Study unearths novel mechanism coordinating the assembly of cell components

New technique for label-free identification of microplastics in human cells

Study results facilitate construction of complex nanoscale computing agents

Formation of transcription factories in living cells resembles the condensation of liquids

Researchers reveal how bacteria make liquid protein droplets to survive harsh environments

Study investigates the role of essential genes in acetic acid tolerance

Novel technique shows molecule conformations in live cells

Metabolic restoration could provide natural protection against HIV

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

New smart microscope developed for the imaging of biological surfaces

Researchers develop a novel sensor to detect chemical changes in immune cells

Researchers reconstitute the biological clock to better understand circadian rhythms

Study offers important insights into how circadian clocks function at the subcellular level

Supercoiling and looping can transmit mechanical stress along the DNA backbone, shows study

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