Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

Black death and the development of immune genes

The Black Death, which wiped off up to 50% of the European population in less than five years, was the single-worst mortality catastrophe in recorded history.

21 Oct 2022

Applying machine learning to define significant immune cells

The method correctly categorizes macrophage states, which is crucial since these cells can alter their behavior and function as either pro- or anti-inflammatory agents during an immune response.

20 Oct 2022

New imaging technologies to evade immune responses of Candida albicans

Researchers from the Monash Biomedicine Discovery Institute have demonstrated how the common fungus Candida albicans evades immune responses using newly discovered imaging technologies. The researchers claim that this involves a fungus that can shape-shift in an “alien-like” manner to escape immune cells.

21 Sep 2022

Researchers demonstrate how tumors make immune cells less effective

Cedars-Sinai Cancer Center scientists found that cancerous tumors known as soft-tissue sarcomas generate a protein that changes immune cells from tumor attacking to tumor-promoting.

27 Jun 2022

Researchers analyze functional microglia to empower retinal organ

Professor Zi-Bing Jin is in charge of this research (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, and Capital Medical University). He has spent the last decade working on retinal organoids, which can accurately mimic retinal development.

3 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Researchers shed light on development and treatment of brain diseases

It is highly regulated what goes into the brain and what does not. The phagocytes that encapsulate the blood arteries in the brain and maintain the blood-brain barrier have been examined by researchers at the University of Freiburg’s Faculty of Medicine.

25 Apr 2022

Manipulating immune cells to suppress the growth of some solid tumors

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages.

21 Apr 2022

Discovery could help break the cycle of rapid transmission of TB

Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers.

18 Apr 2022

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

29 Mar 2022

Researchers use urinary proteomics to detect abnormalities inside the body

Dr Jun Qin, a proteomics expert from the State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, and Dr Zhongde Zhang from The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, worked in the front line of compacting COVID-19 disease.

23 Mar 2022

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an incurable, rare cancer of skin-homing T cells that is highly disfiguring and lethal at advanced stages.

2 Mar 2022

Macrophages restore normal functions when transported back to the body, says research

New research shows that some immune cells could reinstate their regular functions when they are introduced back into the body.

28 Feb 2022

Study decodes the heterogeneity of tumor-infiltrating immune cell composition in diffuse large B-cell lymphoma

In Finland, about 700 people are identified with diffuse large B-cell lymphoma (DLBCL) every year.

24 Feb 2022

Plant-based nanoparticles likely to provide anti-cancer drug

Nanomaterials have transformed cancer therapy, and plant-derived nanoparticles have the added benefit of being cost-effective and simple to produce in mass.

From Tokyo University of Science 16 Feb 2022

Healthy sleep pattern alleviates some of the symptoms of Alzheimer’s disease

According to research, the brain’s capacity to clear a protein closely associated with Alzheimer’s disease is tied to the circadian cycle.

14 Feb 2022

Intracellular pathogens trick the host’s immune system to evade destruction

A signaling mechanism that enables bacteria like Salmonella to escape destruction by the immune system of the host was discovered by scientists.

From The University of California, Davis 14 Feb 2022

New model could improve the assessment of heart disease

A heart attack or stroke can blindside people who thought they were at low risk. Now, research led by UConn Health has found a new model that could improve how we assess heart disease.

1 Feb 2022

Researchers identify changes in gene expression and cellular interactions in COPD lung cells

Researchers at Baylor College of Medicine, Yale University and other institutions have identified previously unrecognized changes in gene expression and cellular interactions in distinct cell populations in chronic obstructive pulmonary disease (COPD).

28 Jan 2022