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New Culture System may Improve Efficiency and Safety of Genome Editing in HSCs

Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets.

11 Jul 2023

Fungal Invasion Threatens Amphibian Biodiversity in North America

According to recent studies, the amphibian biodiversity could suffer greatly if the fungus infection Batrachochytrium salamandrivorans (Bsal) were introduced to North America.

15 Jun 2023

Study Sheds Light on the Genetic Basis for Body Plan Development in the Starlet Sea Anemone

Lacking bones, brains, and even a complete gut, the body plans of simple animals like sea anemones appear to have little in common with humans and their vertebrate kin.

14 Jun 2023

New Stem Cell Technique to Revolutionize Stem Cell Research

Studies of the interaction between human genetics and biology on a wide scale have been made possible by a potent new stem cell technology.

12 Jun 2023

The New Player in ALS—An Ancient, Virus-Like Protein

ALS (amyotrophic lateral sclerosis) is a deadly neurodegenerative disease that attacks nerve cells in the brain and spinal cord, progressively robbing individuals of their capability to speak, move, eat, and breathe.

8 Jun 2023

Fructose is Needed for Enhanced Egg Production in Fruit Flies, Study Reveals

To many people, the sugars we eat may seem like a luxury that can do more harm than good. But now, researchers from Japan have discovered that in insects, dietary sugars play a key role in reproduction.

25 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

23 May 2023

Researchers Publish a Detailed Protocol for Making Three Cell Types From iPSCs

Researchers at NIH's National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.

17 May 2023

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

NIH Common Fund Selects New York Genome Center as Multi-Grant Recipient Under SMaHT Network

The National Institutes of Health (NIH) Common Fund has selected the New York Genome Center (NYGC) as a multi-grant recipient under the Somatic Mosaicism across Human Tissues (SMaHT) Network.

15 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

12 May 2023

Patients With Motor Neuron Disease and Frontotemporal Dementia Carry the Same Genetic Defects

New research has discovered that some patients with motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases.

10 May 2023

Understanding How Supernumerary Chromosomes Arise

The majority of chromosomes have existed for millions of years.

5 May 2023

Study Uncovers Somatic Mutations That Play a Role in Common Form of Adult Epilepsy

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.

2 May 2023

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease?

28 Apr 2023

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

27 Apr 2023

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Artificially synthesizing genomes has numerous applications, including medical research and industrial strains. Scientists are continuously progressing in the depth and breadth of genome design and synthesis, from Craig Venter’s team’s synthesis of the artificial life JCVI-syn1.0 in 2010 to the rewriting and synthesis of the prokaryotic E. coli genome, and the Sc2.0 project’s artificial synthesis of the yeast genome.

26 Apr 2023

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

A breakthrough in gene variants of an inflammation “brake” brings researchers one step closer to developing personalized treatments for those at risk of kidney disease and kidney failure.