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Genome-wide pattern found in glioblastoma tumors predicts patient survival

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) -- the most common and the most aggressive brain cancer -- has simply been age at diagnosis.

15 May 2020

Study reveals nuanced role for oncogene in contact inhibition

Like subway com muters on a crowded train, cells generally prefer not to be packed in too tightly. In fact, they have set up mechanisms to avoid this, a phenomenon called "contact inhibition."

15 May 2020

Discovering a Protein that Controls Brain-Blood Vessel Development

AZoLifeSciences speaks to Professor Long Nam Nguyen about his research which led to the discovery of a protein that controls brain-blood vessel development.

From National University of Singapore (NUS) 15 May 2020

Coronavirus attacking microRNA numbers reduce with age

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

14 May 2020

Researchers identify missing component of innate immune signaling

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans.

14 May 2020

Study shows how plant viral protein disrupts cell division to promote its own propagation

Viruses are ever-present pathogens that lead to severe infectious diseases in humans as well as in agricultural crops.

14 May 2020

A Combo Of Fasting Plus Vitamin C Is Effective For Hard-To-Treat Cancers

Scientists have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C.

14 May 2020

Study reveals proteins that sustain cancer cells

Scientists from the University of Copenhagen have identified two major functions of the protein known as RTEL1 during cell division, in a recently performed study.

14 May 2020

New approach provides closer look at the development of multicellular organisms

Highly complex organisms can arise from a single cell, which is one of the true miracles of nature. Substances known as morphogens have an important role in this development, namely by signaling to cells where they should go and what they should do.

13 May 2020

Breaking Down the DNA Behavior of Cancer Cells

Dr. Manel Esteller speaks to AZoLifeSciences about his ground-breaking cancer research in which he uncovered the behavior of DNA in 3D models.

From University of Barcelona 13 May 2020

Study could help design better methods to create muscle cells from stem cells

A research team has created the world’s first roadmap of the development mechanism of human skeletal muscles, including the development of muscle stem cells.

12 May 2020

Determining effect of drugs in pancreatic islets through single-cell RNA-seq approach

Scientists have developed a technique to assess the impact of particular drugs in pancreatic tissues by using an advanced single-cell RNA sequencing approach.

12 May 2020

Mice study identifies protein vital for liver restoration and regeneration after hepatic surgery

Researchers from the Faculty of Medicine of the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS have identified in a study with mice a protein which is fundamental to guarantee the restoration and regeneration of the liver after a transplant or hepatic surgery.

12 May 2020

Gene therapy builds muscle mass, reduces fat in mice

Exercise and physical therapy often are recommended to help people who have arthritis. Both can strengthen muscle - a benefit that also can reduce joint pain.

12 May 2020

Microbiome 'fingerprint' method helps track microbial strains transferred from maternal to infant gut

Microbial communities in the intestine -- also known as the gut microbiome -- are vital for human digestion, metabolism and resistance to colonization by pathogens.

11 May 2020

Selectively eliminating leukemic and hematopoietic stem cells

Acute myeloid leukemia is an aggressive cancer of the blood-forming system. It affects the hematopoietic stem cells, or blood stem cells, of various white blood cells and of the red blood cells and platelets.

11 May 2020

Stem cells can postpone their own death to aid healing

Already known for their shape-shifting abilities, stem cells can now add "death-defying" to their list of remarkable qualities.

8 May 2020

Novel mechanism allows the immune system to control autoimmunity, cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

7 May 2020

Anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive (ER+) breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

7 May 2020

Researchers demonstrate a potential solution for treating corneal scarring

Infection, inflammation, trauma, disease, contact lenses - all of these and more can lead to corneal scarring, which according to the World Health Organization is a leading cause of blindness worldwide.

7 May 2020