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Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

Infectious bacteria can produce genetic variants among siblings, study finds

A research team from the University of Tübingen and the German Center for Infection Research is investigating how pathogens influence the immune response of their host with genetic variation.

23 Jul 2020

Study sheds light on the role of white blood cells in the developing brain

Whether white blood cells can be found in the brain has been controversial, and what they might be doing used to be complete mystery.

23 Jul 2020

Study explains the compatibility of bacteria and virus in the human gut

The proverb “all things in moderation” holds good not only for food and drink but also for the cluster of microorganisms found inside the human gut.

22 Jul 2020

Hybrid virus infects cells, interacts with antibodies just like COVID-19 virus

Airborne and potentially deadly, the virus that causes COVID-19 can only be studied safely under high-level biosafety conditions.

22 Jul 2020

Study shows flotillin proteins have direct influence on cell membrane structure

Similar to all cells, bacteria have a membrane that protects them from the outside just like skin.

20 Jul 2020

Scientists gain insights into how parasitic bacterium gives rise to lesions

Bacteria of the genus Bartonella are parasites that can be transmitted to humans via insect bites and animal scratches, resulting in an infection known as "bartonellosis." Cat-scratch disease and trench fever are forms of bartonellosis caused by different Bartonella species infecting humans.

17 Jul 2020

Study uncovers virus-specific T cell immunity in recovered COVID-19 and SARS patients

The T cells, along with antibodies, are an integral part of the human immune response against viral infections due to their ability to directly target and kill infected cells.

17 Jul 2020

Microbiologists identify bacteria which feed on manganese

Caltech microbiologists have discovered bacteria that feed on manganese and use the metal as their source of calories. Such microbes were predicted to exist over a century ago, but none had been found or described until now.

16 Jul 2020

Combination of western-style high-fat diet with antibiotic can increase the risk of pre-IBD

Researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre- inflammatory bowel disease.

16 Jul 2020

Healthy microbiome can reduce severity of chickungunya disease

Chikungunya virus, once confined to the Eastern Hemisphere, has infected millions of people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

15 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

University of Alabama at Birmingham researchers have added fresh evidence that early exposure to vaccine-, bacterial- or microbiota-derived antigens has a dramatic effect on the diversity of antibodies an adult mammal will have to fight future infections by pathogens.

14 Jul 2020

Severely injured donor lungs can be recovered using cross-circulation platform

Respiratory disease is the third leading cause of death worldwide, and lung transplantation is still the only cure for patients with end-stage lung disease.

14 Jul 2020

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

14 Jul 2020

Scientists discover new antiviral drug against paramyxovirus

A new antiviral drug that is effective against a broad range of human pathogens in the paramyxovirus family, such as the human parainfluenzaviruses and measles virus, has been discovered by researchers in the Institute for Biomedical Sciences at Georgia State University.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

New mutation in common flu subtype helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

13 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

Researchers discover how good gut bacteria can help reduce heart disease risk

Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: the potential to reduce the risk for heart disease.

9 Jul 2020