Mitochondria News and Research

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Researchers show how the genetic material travels from cell to cell

The genetic material of plants, animals, and humans is well protected in the nucleus of each cell and stores all the information that forms an organism. For example, information about the size or color of flowers, hair or fur is predefined here.

12 Jan 2021

Two cryo-EM studies identify different types of ATP synthase organization

The mitochondrial ATP synthase is energy-converting macromolecular machine that uses the electrochemical potential across the bioenergetic membrane called cristae. This potential is maintained via a membrane curvature that is induced by ATP synthase assembled in dimers.

11 Jan 2021

Researchers report a potential cancer drug that targets mitochondrial function

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read.

23 Dec 2020

Researchers use different colors of light to control gut bacteria genes

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

23 Dec 2020

Anti-hypertension drug prolongs lifespan in C. elegans, research shows

A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life.

21 Dec 2020

Novel compounds may lead to potential treatment for rare terminal childhood illness

Researchers have discovered a method to “rescue” genetically mutated cells, providing opportunities to develop a new treatment for mitochondrial disease.

21 Dec 2020

ECSIT protein can shed light on the origin of Alzheimer's disease

Researchers have found how a protein governs the behavior of proteins associated with the activity in mitochondria, which is impacted in Alzheimer's disease.

17 Dec 2020

Gene therapy and medication can provide certain beneficial effects of physical exercise

Jose Bianco Moreira from NTNU is now convinced that gene therapy can be used to achieve the positive health benefits of physical exercise.

7 Dec 2020

Gasdermin E triggers pyroptosis and involved in pathogen-induced coral death

Pyroptosis is a highly inflammatory form of programmed necrotic cell death that acts as a defense mechanism against the infection of bacterial and viral pathogens. Pyroptosis is executed by gasdermin, a family of pore-forming proteins.

7 Dec 2020

Researchers use super-resolution microscopy to study bacterial infection mechanisms

Expansion microscopy, abbreviated as ExM, allows scientists to image cells and their components with a spatial resolution down to 200 nm.

4 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

New gene therapy can protect visual function in patients with dominant optic atrophy

Researchers have created a novel gene therapy approach that shows promise for someday treating an eye disease that results in progressive vision loss.

27 Nov 2020

Scientists identify new way to turn energy-poor pathway products into biorenewable ones

The imminent environmental crisis calls for an urgent transition to a green economy. A team of scientists at Nagoya University, Japan, led by Professor Susumu Saito, has recently found an interesting way to make this happen -- by leveraging an important metabolic pathway in living cells.

16 Nov 2020

Mitochondria News and Research

Researchers show how the genetic material travels from cell to cell

Two cryo-EM studies identify different types of ATP synthase organization

Researchers report a potential cancer drug that targets mitochondrial function

Researchers use different colors of light to control gut bacteria genes

Anti-hypertension drug prolongs lifespan in C. elegans, research shows

Novel compounds may lead to potential treatment for rare terminal childhood illness

ECSIT protein can shed light on the origin of Alzheimer's disease

Gene therapy and medication can provide certain beneficial effects of physical exercise

Gasdermin E triggers pyroptosis and involved in pathogen-induced coral death

Researchers use super-resolution microscopy to study bacterial infection mechanisms

Drug meant for bacterial infections can combat weight gain

New gene therapy can protect visual function in patients with dominant optic atrophy

Scientists identify new way to turn energy-poor pathway products into biorenewable ones

Study shows statins have different effects on different parts of the body

Cellular senescence variations may help control health and onset of age-related diseases

Ketogenic diets can prevent or reverse heart failure caused by metabolic process

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Researchers discover how synapses find energy to support intense neural conversations

Study explains the organization of genetic information contained within mitochondria

Alzheimer's disease may be driven by overactivation of fructose made in the brain

Exploring the Genetic effects of Chernobyl Radiation

Genomic Analysis for the Conservation of Koalas

Developing a portable tool to detect street drug ‘spice’

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