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Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Sustainable dietary habits are linked to health benefits, says study

Large population research from Lund University in Sweden has revealed that sustainable dietary habits are associated with health benefits like a decreased risk of premature death from cancer and cardiovascular disease.

13 Dec 2021

Commonly used drugs have powerful effects on the gut microbiome, research shows

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute the highest cause of mortality worldwide.

9 Dec 2021

Study identifies how embryonic cells detect stiffness in their environment

According to recent research by UCL scientists, cells in the developing embryo sense the stiffness of other cells surrounding them, a vital factor that makes them move together to form the skull and face.

From University College London 9 Dec 2021

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

1 Dec 2021

Tackling pollution from ammonia emissions could reduce many premature deaths

Tackling pollution from the emission of nitrogen compounds, particularly ammonia, could reduce many of the 23.3 million years of life that were lost prematurely across the world in 2013 due to nitrogen-related air pollution, an international study led by Chinese scientists has discovered using a modeling framework, including the IIASA GAINS model.

5 Nov 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

Human-induced environmental change affects animals' behavioral traits

Humans are shaping environments at an accelerating rate. Indeed, one of the most important current topics of research is the capacity of animals to adapt to human-induced environmental change and how that change affects the expression of animal traits.

20 Oct 2021

Infection with measles virus activates two different immune responses

Researchers from The University of Tokyo Institute of Industrial Science have found that infection with the measles virus activates not one but two different branches of the innate immune system.

15 Oct 2021

Long-term exposure to low concentrations of air pollution may increase mortality risk

Exposure to low concentrations of air pollution, even at levels permitted under federal regulations, may be causing tens of thousands of early deaths each year among elderly people and other vulnerable groups in the U.S., according to a large national study from Harvard T.H. Chan School of Public Health.

8 Oct 2021

Scientists find two proteins that pair up to build lifelines to cancer cells

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

21 Sep 2021

New Cornell study finds potential treatment for MRSA ‘superbug’

A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.

17 Sep 2021

Poor systemic immune responses and elevated MAIT cell activation linked to fatal COVID-19 infections

The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological factors associated with death in critically ill COVID-19 patients are poorly understood.

17 Sep 2021

Pairing microscopy with AI to develop a rapid, accurate COVID-19 test

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

13 Sep 2021

Vaccines remain highly effective against new COVID-19 Delta variant

COVID-19 vaccines are effective at preventing hospitalizations and emergency department visits caused by the Delta variant, according to data from a national study.

13 Sep 2021

Family of naturally occurring proteins shows promise for treating ischemic stroke

Boosting a family of naturally occurring proteins that dampens inflammation in the body has been shown to be effective in reducing damage from an ischemic stroke, according to preclinical researchers at The University of Texas Health Science Center at Houston.

2 Sep 2021

Scientists isolate monoclonal antibodies against alphaviruses

A research group has isolated monoclonal antibodies that, in laboratory and animal studies, prohibited infection by alphaviruses.

From Vanderbilt University 24 Aug 2021

Study identifies variants and genes linked to alcohol consumption

Scientists from the Icahn School of Medicine at Mount Sinai published the first of its kind research in the field of addiction genetics employing a multi-omics method to offer a huge list of causal candidate genes linked with alcohol consumption and alcohol use disorder (AUD).

24 Aug 2021