Multiple sclerosis (MS) is a severe autoimmune disease of the central nervous system that affects the brain and spinal cord, causing problems with muscle movement, balance and vision.
Throughout a person’s life, many stimuli can turn on and off many of the genes, resulting in the variances that distinguish people.
Researchers from University of British Columbia and Michigan State University have invented a system that can quickly and inexpensively detect airborne viruses using the same technology that enables high-speed trains.
Viral genetic remnants found naturally in the human genome may influence the development of neurodegenerative diseases.
Most of us who've reached middle age have noticed a slowing in memory and cognition, but scientists don't have a clear picture of the molecular changes that take place in the brain to cause it.
Research of over 22,000 patients with multiple sclerosis (MS) has for the first time discovered a genetic variant linked with speedier progression of the disease, a buildup of disability that can deprive patients of their mobility and independence over time.
A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.
Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.
When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.
In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).
The spinal cord acts as a messenger, carrying signals between the brain and body to regulate everything from breathing to movement.
Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).
Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.
Inflammatory neurological diseases, such as multiple sclerosis (MS), can arise when cell-to-cell communication between cells in the central nervous system (CNS) goes awry. But exactly how this cellular crosstalk leads to the molecular changes that drive disease remain unknown.
Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.
Among the most promising areas of scientific inquiry is the study of the human microbiome and its effect on health. To fuel more rapid progress in this field, Andrea and Donald Goodman and Renee and Meyer Luskin have made a $20 million gift to establish the UCLA Goodman–Luskin Microbiome Center.
Discrepancies in the gut microbiomes of people having myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) than those of healthy controls have been disclosed by newly performed research.
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that the share of promotional spending allocated to consumer advertising was on average 14.3 percentage points higher for drugs with low added benefit compared to drugs with high added benefit.
Four genetic mutations have been linked to progressive multifocal leukoencephalopathy (PML), a rare but sometimes fatal brain infection that can be provoked by dozens of FDA-approved drugs.
Transplanting blood stem cells is a new but incredibly successful treatment for multiple sclerosis. Now, a study directed by the University of Zurich has looked closely at how the autoimmune disease is controlled by the treatment and how the immune system recovers afterward.
Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.