Mutation News and Research

RSS

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

Study adds two new genetic variants to the list of glutamate receptor mutations

Researchers from Northwestern Medicine distinguished different variants of the gene GRIK2 that induces nonsyndromic neurodevelopmental disorder (NDD).

27 Sep 2021

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

Scientists at La Jolla Institute for Immunology have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates.

24 Sep 2021

Study reveals how the tumor suppressor gene plays a vital role in pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

20 Sep 2021

Combining bacteriophages with antibiotics to treat antibiotic-resistant infections

Mycobacterium abscessus, a relative of the bacteria that cause tuberculosis and leprosy, is responsible for particularly severe damage to human lungs and can be resistant to many standard antibiotics, making infections extremely challenging to treat.

17 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Loss of natural HIV control preceded by functional impairment of T cells

HIV is a master of evading the immune system, using a variety of methods to prevent the body from being able to find and kill it.

13 Sep 2021

Study imparts mechanistic understanding on early stages of human cancer

Scientists demonstrated that normal human fibroblast cells can be converted to specific cancer cells through factors that are identified in actual human patients.

9 Sep 2021

Study details replication and immune evasion of Delta SARS-CoV-2 variant

According to scientists, the Delta variant of SARS-CoV-2 has likely spread through its capability to avoid neutralizing antibodies and its heightened infectivity.

8 Sep 2021

New approach could lead to better treatments for mitochondrial diseases

Mutant DNA sequences inside cellular mitochondria can be eliminated using a bespoke chemical compound. The approach, developed by scientists at Kyoto University's Institute for Integrated Cell-Material Science (iCeMS) in Japan, could lead to better treatments for mitochondrial diseases.

31 Aug 2021

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

24 Aug 2021

Study reveals the biology and treatment behind rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

20 Aug 2021

Mutation News and Research

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Study adds two new genetic variants to the list of glutamate receptor mutations

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

Study reveals how the tumor suppressor gene plays a vital role in pediatric rhabdomyosarcoma

Combining bacteriophages with antibiotics to treat antibiotic-resistant infections

Researchers reveal why nerve cell’s protein production slows down in CMT patients

Loss of natural HIV control preceded by functional impairment of T cells

Study imparts mechanistic understanding on early stages of human cancer

Study details replication and immune evasion of Delta SARS-CoV-2 variant

New approach could lead to better treatments for mitochondrial diseases

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Study reveals the biology and treatment behind rare rheumatoid-like autoinflammatory condition

Novel genome-editing technology to mitigate Alzheimer’s disease

Study describes a new method for identifying sperm mutations that can cause disease in children

New system solves 3D structures of RNA-only molecules with unprecedented speed and accuracy

New technique to hunt down mutations that cause cancer drug resistance

Experimental small molecule could help treat Parkinson’s disease in future

Study reveals melanoma is associated with a chemical conversion in DNA

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

New thin-film microfluidic device to manipulate β-lactoglobulin in milk

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics