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Scarring on the Extracellular Matrix Causes Muscles to Stop Working in Duchenne Muscular Dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

12 May 2023

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

12 May 2023

How the Natural Process of DNA Repair Fails to Cause Disease

We often come to an understanding of what causes a disease. We know, for example, that cancers are caused by mutations at critical locations in the genome, resulting in loss of control of cell growth.

11 May 2023

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact.

9 May 2023

Researchers Advance the Breeding of High-Resistant Starch Rice

Researchers have demonstrated that the loss of function of two paralogous starch biosynthesis genes increases the amount of resistant starch (RS) in cooked rice.

8 May 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Despite the astounding advances made in understanding the biologic underpinnings of cancer, many cancers are missing obvious genetic drivers.

5 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

4 May 2023

Study Reveals How the Formation of Microtubules Drives Cell Division

Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment.

2 May 2023

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease?

28 Apr 2023

New Gene Therapy may be on the Horizon for Usher Syndrome Type 1F

Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.

27 Apr 2023

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

When the first symptoms of Parkinson’s disease are experienced by a patient, the disease has been evolving for a long period, and the patient might already have lost half of a certain kind of nerve cells in the brain.

27 Apr 2023

New Genetic Mutations Linked to Canine Bladder Cancers Identified

Researchers have identified new genetic mutations linked to a subset of canine bladder cancers. Their findings have implications both for early cancer detection and for targeted treatments in dogs and humans.

26 Apr 2023

Interpreting Mutations in Disease Genes and Improving Clinical Decision-Making

DeMAG is a new method that was developed by Max Planck and Harvard’s research team. It is a new technique that has been shared as an open-source web server (demag.org) to assist interpret mutations in disease genes and enhance clinical decision-making.

26 Apr 2023

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

24 Apr 2023

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

At St Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard, researchers have shown how prime editing could help correct the mutation that results in sickle cell disease in a possibly curative method.

18 Apr 2023

UH Researcher Designs New Model Expressing the Most Common Disease Mutation in USH2A

Usher syndrome, a rare inherited genetic disease, is a leading cause of combined deafness and blindness with type 2A (USH2A) being the most common form.

18 Apr 2023

Entry of Aging-Associated Enzymes into Human Genetic Material

An enzyme that controls aging and other metabolic processes accesses human genetic material to modify gene expression within the cell, according to a new study. Images of a sirtuin enzyme bound to a nucleosome, a tightly packed complex of DNA and proteins called histones, have been created by a team led by Penn State researchers.

17 Apr 2023

Mutation News and Research

Scarring on the Extracellular Matrix Causes Muscles to Stop Working in Duchenne Muscular Dystrophy

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

How the Natural Process of DNA Repair Fails to Cause Disease

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Researchers Advance the Breeding of High-Resistant Starch Rice

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Innate Tumor Suppression Mechanism Uncovered

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

Mini Organs Provide New Insights Into Fibrolamellar Carcinoma

Study Reveals How the Formation of Microtubules Drives Cell Division

Research Shows How Mammalian Genomes Have Developed Over the Course of Evolution

New Gene Therapy may be on the Horizon for Usher Syndrome Type 1F

Getting Insights into Parkinson’s Patients’ Brain Cells Through Stem Cell Research

New Genetic Mutations Linked to Canine Bladder Cancers Identified

Interpreting Mutations in Disease Genes and Improving Clinical Decision-Making

Genetic Variant Linked to Increased Risk of Developing Perianal Crohn's Disease

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

UH Researcher Designs New Model Expressing the Most Common Disease Mutation in USH2A

Entry of Aging-Associated Enzymes into Human Genetic Material

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

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