Neurons News and Research

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Patients With Motor Neuron Disease and Frontotemporal Dementia Carry the Same Genetic Defects

New research has discovered that some patients with motor neuron disease (MND) and frontotemporal dementia (FTD) carry the same rare genetic defects that cause other neurodegenerative diseases.

10 May 2023

Experimental Model Sheds Light on Key Cellular Processes Involved in Embryogenesis

Many birth defects and spontaneous abortions occur during the embryonic development stage known as neurulation, yet we have very little insight into how this critical developmental process unfolds in humans.

9 May 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.

5 May 2023

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Worms may not be depressed. However, this does not prevent them from benefiting from antidepressants.

5 May 2023

Texas A&M Research Provides a Definitive Answer to the Evolutionary Timeline of Mammals

Research led by a team of scientists from the Texas A&M School of Veterinary Medicine and Biomedical Sciences puts to bed the heated scientific debate regarding the history of mammal diversification as it relates to the extinction of the non-avian dinosaurs.

2 May 2023

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

2 May 2023

Reprogramming the Aging Process to Effectively Promote Longevity

Human lifespan is associated with the aging of individual cells. Three years ago, a group of researchers from the University of California, San Diego, uncovered fundamental mechanisms underlying the aging process.

28 Apr 2023

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

28 Apr 2023

Study Finds Link Between Chemical "Marks" on DNA in Father’s Sperm and Autistic Traits in Children

Among families with children diagnosed with autism spectrum disorder, Johns Hopkins University researchers say they have found a link between chemical "marks" on DNA in the sperm of fathers and autistic traits in their 3-year-old children.

28 Apr 2023

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

The April 2023 issue of SLAS Discovery contains six full-length articles and one mini-review covering high-throughput screening (HTS) for protease-inhibiting drugs, high-content phenotypic screening and other life sciences research.

28 Apr 2023

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function.

27 Apr 2023

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

26 Apr 2023

A Study on Neural Crest Cell

As per a new study from the University of Bath, a neural crest cell (a kind of stem cell) starts with the capacity to differentiate into numerous specialist cell kinds, but it also seems to retain the ability to “change its mind” and differentiate again when the situations are appropriate.

26 Apr 2023

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

The mathematical and biological mechanisms underlying the rugged structures at cell boundaries present in tissues like the kidneys and nasal glands have been discovered.

26 Apr 2023

Researchers Illuminate How Neurons Consume and Metabolize Glucose

The human brain has a sweet tooth, burning through nearly one quarter of the body's sugar energy, or glucose, each day.

21 Apr 2023

Engineered Sustainable, Patient-Specific NPCs Could Help Treat Neurodegenerative Diseases

Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson's disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa.

21 Apr 2023

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

People with dementia have protein build-up in astrocytes that may trigger abnormal antiviral activity and memory loss, according to a preclinical study by a team of Weill Cornell Medicine investigators.

21 Apr 2023

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

20 Apr 2023

Neurons News and Research

Patients With Motor Neuron Disease and Frontotemporal Dementia Carry the Same Genetic Defects

Experimental Model Sheds Light on Key Cellular Processes Involved in Embryogenesis

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Texas A&M Research Provides a Definitive Answer to the Evolutionary Timeline of Mammals

Understanding the Process of Gene Regulation Using Cryogenic Electron Microscopy

Reprogramming the Aging Process to Effectively Promote Longevity

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

Study Finds Link Between Chemical "Marks" on DNA in Father’s Sperm and Autistic Traits in Children

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

Computational Models can Help Determine the Identities and Roles of Individual Neurons

A Study on Neural Crest Cell

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

Researchers Illuminate How Neurons Consume and Metabolize Glucose

Engineered Sustainable, Patient-Specific NPCs Could Help Treat Neurodegenerative Diseases

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

DSCAM Gene Triplication Causes Excessive Inhibitory Signaling in the Brain of Down Syndrome Mouse

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

The Last Piece of Our Genome: Sequencing the Y Chromosome

Understanding the Importance of Entrepreneurship in the Life Sciences Community

Supporting Informed Decisions on Malaria Biocontrol Interventions

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