Nucleic Acid News and Research

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ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Multidisciplinary approaches for data management in omics research

Bioinformatics, and by extension omic sciences - the collective disciplines that are dependent on the use of extensive datasets of biological information - present a challenge of data management for researchers all over the world.

25 Feb 2021

Scientists discover new class of compounds for combating antimicrobial resistance

Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature.

24 Dec 2020

Novel technique enables the study of non-bacterial microbiomes of plant species

A new method designed by plant pathologists in Connecticut now allows researchers to access an effective and low-cost tool to facilitate the analysis of the all non-bacterial microbiomes of all plant species.

11 Dec 2020

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care.

11 Dec 2020

Scientists use honey bee peptide to design RBC carriers that deliver therapeutic proteins

Most often, protein therapies are more selective and potent toward their biochemical targets when compared to other types of medicines, specifically small molecules.

10 Dec 2020

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour.

4 Dec 2020

Study underlines the significance of epithelial against invasive pathogens

Researchers have demonstrated that a protein present in skin cells detects a particular nucleic acid that is developed at the time of virus replication.

30 Nov 2020

Warwick researchers design computational model to enable drug predictions against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

From The University of Warwick 26 Nov 2020

Scientists identify potential targets against coronavirus

Scientists comprehensively studied the RNA genomic structure of the SARS-CoV-2 coronavirus.

11 Nov 2020

Highly automated device rapidly detects the presence of COVID-19

Throughout the pandemic, infectious disease experts and frontline medical workers have asked for a faster, cheaper and more reliable COVID-19 test.

6 Nov 2020

Porvair Sciences offers optimized microplate for SARS-CoV-2 nucleic acid purification

Porvair Sciences has introduced a new 2.2ml 96 deep well plate specifically designed to be fully compatible with the Thermo Scientific™ KingFisher™ range of nucleic acid purification systems.

From Porvair Sciences Limited 2 Nov 2020

Exploiting CRISPR systems for the fast detection of SARS-CoV-2

A paper published on medRxiv describes a repurposed type III CRISPR-Cas system that can detect the virus from nasopharyngeal swabs in less than an hour.

26 Oct 2020

Researchers develop a new method for siRNA stabilization

In the gene controlling mechanism, known as RNA interference, the expression of particular genes is downregulated by siRNAs or endogenic microRNAs.

19 Oct 2020

Krystal binding microplates set a new standard for uniform, reproducible capture of biomolecules

Porvair Sciences new medium and high bind Krystal microplates set a new standard for uniform and reproducible capture of a wide range of biomolecules ready for affinity binding assays such as ELISA's.

From Porvair Sciences Limited 16 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Researchers develop low-cost CRISPR method to detect SARS-CoV-2

In March 2020, scientists started to design a new, cost-efficient, CRISPR-based diagnostic platform to spot infectious diseases, such as SARS-CoV-2.

22 Sep 2020

Combined point-of-care nucleic acid and antibody test can speed up COVID-19 detection

A Cambridge hospital has piloted the use of combined rapid point-of-care nucleic acid and antibody testing for SARS-CoV-2 infection after researchers at the University of Cambridge showed that this approach was superior to virus detection alone for diagnosing COVID-19 disease.

3 Sep 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Researchers identify key enzyme that drives the production of ribosomes

Scientists have demonstrated that an enzyme fuels the production of ribosomes—the molecular machines that synthesize all cellular proteins.

From University of Toronto 17 Jul 2020