Nucleotides News and Research

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Therapeutic mRNAs do not significantly impact translational fidelity

Synthetic mRNA therapeutics for the treatment and prevention of disease has attracted a lot of interest due to the exceptional efficacy of mRNA vaccinations against SARS-CoV-2.

30 Aug 2022

Novel fluorescent probe likely to help decode neuronal talking

Numerous cells, including neurons, depend on the intracellular messenger molecule cyclic adenosine monophosphate (cAMP) to function. It does this by encouraging axon growth and maintaining neuronal communication.

15 Jul 2022

Online version algorithm helps to detect ramp sequences of RNA, study finds

The significance of detecting and comprehending how variations between tissues and cells influence gene expression without altering the underlying genetic code is discussed in a recent study by University of Kentucky researchers.

1 Jul 2022

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

1 Jul 2022

Researchers develop a new biochemical process to analyze plant immunity

Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.

27 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

New open-source tool automates RNA analysis, likely to encourage research and drug development

Scripps Research scientists have introduced a new software tool for examining RNA (ribonucleic acid) molecules, which play a variety of important roles in living things.

10 May 2022

Max Planck researchers reveal the structure of kinetochore corona

During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells.

11 Apr 2022

Scientists develop low-cost metagenome sequencing technique for microbiome research

A research team headed by the Chinese Academy of Sciences, QIBEBT developed a low-cost metagenome sequencing technology.

31 Jan 2022

Researchers propose new approach for plant genome sequencing

A new study carried out by the Fort Worth-based Botanical Research Institute of Texas shows how plant genomics has progressed.

24 Jan 2022

Unraveling how DNAzymes work in real time

DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain.

23 Dec 2021

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Researchers develop artificial genomic DNA capable of replication and evolution

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous replication extracellularly using cell-free materials alone, such as nucleic acids and proteins for the first time.

22 Nov 2021

New program can help to correctly interpret the genetic code of newly sequenced organisms

Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She wondered how genetic code, once thought to be universal, could evolve and change.

10 Nov 2021