Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.
Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.
Metabolites are essentially organic molecules that are formed or participate during the biochemical reactions that continuously occur in an organism.
Diets rich in healthy and plant-based foods encourage the presence of gut microbes that are linked to a lower risk of common illnesses including heart disease, research has found.
Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.
In recent years, the number of high-risk groups for ischemic diseases such as critical limb ischemia where tissues of toe may decay is increasing due to increase in the number of people with obesity, diabetes, and hypertension which are triggered by changes in dietary habits, and consumption of smoking and alcohol.
Texas Biomedical Research Institute Associate Professor Corinna Ross, PhD, is a principal investigator on a $3.38 million National Institutes of Health multi-investigator grant to study "microbiome-mediated therapies for aging and healthspan" in marmosets, which are small monkeys native to South America and are becoming increasingly more important in aging and infectious disease research.
The spread of SARS-CoV-2, the coronavirus responsible for the current pandemic outbreak, has been speculated to be linked to short-term and long-term atmospheric pollutants exposure, mainly particulate matters (PMs).
Plastics contain and leach hazardous chemicals, including endocrine-disrupting chemicals (EDCs) that threaten human health.
Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or "gut."
Researchers at the University of Colorado Anschutz Medical Campus have discovered that fructose stimulates the release of vasopressin, a hormone linked to obesity and diabetes.
Researchers from Tokyo Medical and Dental University (TMDU) identify a novel mechanism by which periodontal disease may cause diabetes
Exposure to the widely used weed-killer glyphosate makes genetic changes to rats that can be linked to increased disease in their grandchildren and great-grandchildren, a new study has found.
Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival.
A clinical study with 1002 patients with heart disease shows the advantages of a Mediterranean diet compared to a low-fat diet.
In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.
A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.
The production of fat in the human body is essentially regulated by gut hormones.
A hormone that can suppress food intake and increase the feeling of fullness in mice has shown similar results in humans and non-human primates, says a new study published today in eLife.
There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.
There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.
According to the World Health Organization, obesity has nearly tripled worldwide since 1975. In 2016, for example, more than 1.9 billion adults were categorized as overweight. Of these, more than 650 million had obesity.