Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.
Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.
Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.
Cells move constantly throughout our bodies, performing myriad operations critical to tissue development, immune responses, and general wellbeing. This bustle is guided by chemical cues long studied by scientists interested in cellular migration.
Researchers have shown that the advanced CRISPR/Cas9 system is extremely effective in curing metastatic cancers.
Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.
Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.
Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.
Climate change will bring an acute toll worldwide, with rising temperatures, wildfires and poor air quality, accompanied by higher rates of cancer, especially lung, skin and gastrointestinal cancers, according to a new report from UC San Francisco.
Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine.
Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.
Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.
In breakthrough colon cancer research, scientists at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE.
An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice.
Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.
Despite the remarkable successes of immune-based treatments for cancer, not everyone responds to these approaches and relapses do occur.
Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.
The evolution of the refined human immune system has turned into an effective defense system against several diseases, including cancer.
The cover for issue 30 of Oncotarget features Figure 4, "RNAseq results demonstrating differences between normal, cancer, and redirected cells," by Frank-Kamenetskii, et al. which reported that the influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not.
Researchers have designed a laboratory test that can precisely examine the deadliest cells found in the most common and aggressive type of brain cancer.
The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread. Two of the most commonly altered genes in cancer are p53 and AKT.