Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.
More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).
Scientists have grown ‘mini-placentas’ in the lab and used them to see how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.
The Hubrecht Institute's Organoid group created the first organoid model of the human conjunctiva. The function of these organoids is mimicked by the human conjunctiva, a tissue involved in the formation of tears.
In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.
Dozens of science and technology development payloads returned to Earth from the International Space Station (ISS) on December 22 as SpaceX’s 29th Commercial Resupply Services (CRS) mission, contracted by NASA, successfully concluded.
Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.
Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.
Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids' development.
Stem cells possess the remarkable ability to differentiate and replace deceased or impaired cells within the body.
In the realm of scientific research, particularly in the medical and pharmaceutical sectors, animal testing has been a prevalent method.
The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.
In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.
When a cell dies, a new one has to be formed in its place. This is a regular occurrence in the intestines, where cells are especially exposed to harmful effects.
Researchers at ETH Zurich have created a technique that enables them to genetically alter every animal cell in a unique way.
Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative.
Investigators are learning more about how schizophrenia develops by investigating the most powerful known genetic risk factor.
Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.
Researchers have developed a synthetic extracellular matrix (ECM) that can facilitate the development of a miniature endometrium in a dish for at least two weeks.
Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.
According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.