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Cell Adhesion Mechanisms Behind Endometriosis Spread

The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to combat endometriosis effectively.

2 Jul 2025

Genetic Ancestry Tied to Immune Response in Dengue Infection

For the first time, the extreme variability in dengue fever has been linked to a biological mechanism, potentially opening doors to new treatments and vaccines for the most common mosquito-borne disease worldwide.

1 Jul 2025

Scientists Grow Liver Organoids with Functional Blood Vessels

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology--producing liver tissue that grows its own internal blood vessels.

26 Jun 2025

New Study Hints at Customizable Chili Heat and Pain Relief

A new study identifying molecules that reduce the heat of chili peppers suggests the potential to develop these compounds into an “anti-spice” condiment for excessively spicy foods.

23 May 2025

Single Cell Sequencing Uncovers Hidden Drivers of Severe Celiac Disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

17 May 2025

Study Reveals T Cell Plasticity as a Key Driver of Systemic Autoimmunity

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

5 May 2025

New Genetic Discoveries Offer Hope for Osteoarthritis Treatments

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

29 Apr 2025

New Scientific Article in Nature Linking the Potential Use of NeuroRestore ACD856 for the Treament of Obesity

AlzeCure Pharma AB (publ) (FN STO: ALZCUR), a pharmaceutical company that develops candidate drugs for diseases affecting the nervous system, focusing on Alzheimer's disease and pain, announced today that an article has been published in Nature suggesting the use of NeuroRestore ACD856 in the treatment of obesity.

2 Apr 2025

Unlocking CBD’s Potential with Phospholipid Tech

Research shows phospholipid complexation enhances CBD's solubility and absorption, paving the way for more effective treatments for epilepsy and chronic pain.

26 Mar 2025

Allegro’s Injectable Osteoarthritis Treatment Generates Positive Safety Results in Preclinical Studies

Allegro NV, a biomedical company developing transformative nanotechnology-based treatments for degenerative joint disease, has found that hydrocelin (ALG-001), its injectable microparticle hydrogel, showed no signs of toxicity in two preclinical studies conducted for periods of 4 and 13 weeks respectively.

25 Mar 2025

Study Reveals How Syngap1 Gene Affects Touch-Based Perception in Mice

You may scarcely notice it, but much of what you do every day requires your brain to engage in perceptual learning.

14 Mar 2025

New Cannabinoid Drug Brings Hope For Treating Chronic Pain Without Addiction

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

13 Mar 2025

Pain and Itch Processed by Distinct Neurons in the Anterior Cingulate Cortex

A research team led by KAANG Bong-Kiun, director of the Center for Cognition and Sociality within the Institute for Basic Science (IBS), and KO Hyoung-Gon, professor at Kyung Hee University College of Dentistry, have uncovered the neural mechanisms underlying the processing of pain and itch in the anterior cingulate cortex (ACC).

5 Mar 2025

Synthetic Microbiome Treatment Prevents C. difficile Infection in Mice

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

4 Mar 2025

Viking Skulls Show Evidence of Disease and Painful Conditions

Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more.

24 Feb 2025

Can Mechanochemistry Provide Greener Options for Pharmaceutical Manufacturing?

This study reveals efficient synthesis of ibuprofen:nicotinamide co-crystals via mechanochemistry, highlighting sustainability in pharmaceutical production.

27 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Extracellular Vesicles from Mesenchymal Stromal Cells Restore Joint Health in Osteoarthritis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 22, 2024, entitled, "Anti-aging effect of extracellular vesicles from mesenchymal stromal cells on senescence-induced chondrocytes in osteoarthritis."

20 Dec 2024

Unveiling Human Stem Cell Model with Functional Notochord

For the first time, the notochord a tissue in the developing embryo that serves as a navigation system, telling cells where to build the spine and nervous system (the trunk) has been included in human stem cell models created by researchers at the Francis Crick Institute.

19 Dec 2024