Palindromic Repeats News and Research

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New Culture System may Improve Efficiency and Safety of Genome Editing in HSCs

Hematopoietic stem cells (HSCs) are rare cells found in the bone marrow that produce red blood cells, white blood cells, and platelets.

11 Jul 2023

Dual CRISPR Gene Drive Systems Target a Specific Gene

According to recent research from North Carolina State University, scientists have created a “homing gene drive system” based on CRISPR/Cas9 that could be used to suppress populations of Drosophila suzukii vinegar flies—so-called “spotted-wing Drosophila” that severely damage soft-skinned fruit in North America, Europe, and parts of South America.

13 Jun 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

CRISPR/Cas method could help save rice crops threatened by climate change

A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible 'savior' for rice crops threatened by climate change and high food demand.

3 Mar 2023

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

Highlighting the potential of new techniques to study mental disorders

Researchers investigating the fundamental brain mechanics of autism spectrum disorder have discovered that a gene mutation known to be connected with the illness causes considerably more overstimulation of brain cells than in neuronal cells without the mutation.

23 Nov 2022

Chromosome restructuring suppresses meiotic recombination

The use of CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats) molecular scissors enables targeted editing, insertion, or suppression of genes in plants.

21 Sep 2022

Study describes the importance of the autoimmune response in bacteria

CRISPR has made headlines in recent years for its potential to help patients with conditions as diverse as blindness and sickle cell disease. However, bacteria were already using CRISPR as an immune system to combat viruses long before humans adopted it to combat genetic disorders.

3 Jun 2022

New chemical technique with CRISPR gene-editing tool helps to cure genetic diseases

CRISPR, a gene-editing technique that allows scientists to mend the DNA of human cells almost as easily as using a pair of scissors, has boosted biological and medical research in the last decade.

23 May 2022

New supramolecular CRISPR–Cas9 carrier supports much effective genome editing

Clustered regularly interspaced short palindromic repeats (CRISPR) and their accompanying protein, CRISPR-associated protein 9 (Cas9), several years ago, made international news as a game-changing genome editing system.

18 May 2022

Researchers propose a new fusion method in gene editing to reduce DNA sizes

Researchers who are working on CRISPR/Cas9-mediated gene-editing technology have developed a technique to boost editing performance by reducing DNA deletion sizes.

3 May 2022

Services to accelerate genome editing research

AMSBIO has expanded its range of custom gene editing services to complement its extensive portfolio of off-the-shelf CRISPR/Cas9 products.

From AMS Biotechnology 17 Dec 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

Genome editing technologies can help understand disease-associated genetic mutations

Scientists have developed novel genome-editing technology that could help understand disease-related genetic mutations based on C-to-G single base variations.

27 Jul 2020

Using CRISPR/Cas molecular scissors to recombine entire chromosomes

The CRISPR/Cas molecular scissors work like a fine surgical instrument and can be used to modify genetic information in plants.

27 May 2020

Single-cell gene expression studies can shed more light on disrupted genes

Scientists can gain a better understanding of the cellular roles of the disrupted gene by disturbing the expression of a specific gene and tracking how this change has an impact on the expression of other types of genes.

13 May 2020

New CRISPR technology targets thousands of genes

Thanks to CRISPR-based genetic screens, researchers were able to detect genes that play a major role in lung cancer metastasis, cancer immunotherapy, sickle-cell anemia, and a host of other medical disorders.

18 Mar 2020