Pathophysiology News and Research

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Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Abnormalities in cholesterol transport protein associated with schizophrenia

Scientists have suspected mutations in a cellular cholesterol transport protein are associated with psychiatric disorders, but have found it difficult to prove this and to pinpoint how it happens.

29 Dec 2020

Researchers create 3D miniature organs that precisely mimic human tissues

Organoids are tissues that look like organs and are extracted from stem cells cultured in laboratories. They are usually known as miniature organs.

21 Dec 2020

Molecular markers in the blood can predict severe COVID-19 outcomes

Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team.

15 Dec 2020

Researchers use new decoding method to identify novel proteins encoded by HSV-1

Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.

8 Dec 2020

Study shows cocaine use in mice leads to formation of synapses

Drugs of abuse, like cocaine, are so addictive due in part to their cellular interaction, creating strong cellular memories in the brain that promote compulsive behaviors.

16 Oct 2020

Study helps explain how Treg cells prevent autoimmunity, dampen immune responses

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

22 Sep 2020

Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Using a detailed genetic analysis, a research team from Japan-based Kumamoto University has discovered that the NSD2 enzyme, which controls the actions of several genes, also functions to block the aging of cells.

10 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020