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Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New study shows how T cells function in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

27 Jul 2020

Researchers recreate pancreatic tissue 'in vitro' using 3D cell culture technique

Pancreatic cancer is a life-threatening disease with very poor survival rates in patients, and--despite various efforts--its treatment remains challenging.

23 Jul 2020

Molecular landscape of myelodysplastic/myeloproliferative neoplasms revealed

Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) is a group of rare malignancies with overlapping features from myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN), that include a variety of diseases depending on their phenotype (hematological and morphological characteristics).

3 Jul 2020

Plant tissue succulence engineering can be used to improve drought and salinity tolerance

After several years of experimentation, scientists have engineered thale cress, or Arabidopsis thaliana, to behave like a succulent, improving water-use efficiency, salinity tolerance and reducing the effects of drought.

3 Jul 2020

Even the sickest COVID-19 patients produce T cells to fight back the virus

A new study from researchers at La Jolla Institute for Immunology and Erasmus University Medical Center shows that even the sickest COVID-19 patients produce T cells that help fight the virus.

1 Jul 2020

Function-Based Sequencing Technique Permits Analysis Of Just A Single Bacteria Cell

A function-based sequencing technique using optical tweezers and taking advantage of the properties of gravity is letting researchers analyze bacteria cells.

29 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Study shows promise for treating developmental and epileptic brain disease

Studies show that a pair of mutations detected in people with developmental and epileptic brain disease can be traced back to the same ion channel.

19 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020

Study demonstrates the role of p53 gene in cell cycle regulation and apoptosis

The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.

2 Jun 2020

ADHD-associated genetic variants have reduced progressively in human lineage

According to a study published in the Scientific Reports journal, the frequency of genetic variants linked to attention-deficit/hyperactivity disorder (ADHD) has reduced progressively in the evolutionary human lineage from the Palaeolithic to the present day.

29 May 2020

Study highlights crucial role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

28 May 2020