Phenotype News and Research

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Molecular landscape of myelodysplastic/myeloproliferative neoplasms revealed

Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) is a group of rare malignancies with overlapping features from myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN), that include a variety of diseases depending on their phenotype (hematological and morphological characteristics).

3 Jul 2020

Plant tissue succulence engineering can be used to improve drought and salinity tolerance

After several years of experimentation, scientists have engineered thale cress, or Arabidopsis thaliana, to behave like a succulent, improving water-use efficiency, salinity tolerance and reducing the effects of drought.

3 Jul 2020

Even the sickest COVID-19 patients produce T cells to fight back the virus

A new study from researchers at La Jolla Institute for Immunology and Erasmus University Medical Center shows that even the sickest COVID-19 patients produce T cells that help fight the virus.

1 Jul 2020

Function-Based Sequencing Technique Permits Analysis Of Just A Single Bacteria Cell

A function-based sequencing technique using optical tweezers and taking advantage of the properties of gravity is letting researchers analyze bacteria cells.

29 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Study shows promise for treating developmental and epileptic brain disease

Studies show that a pair of mutations detected in people with developmental and epileptic brain disease can be traced back to the same ion channel.

19 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020

Study demonstrates the role of p53 gene in cell cycle regulation and apoptosis

The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.

2 Jun 2020

ADHD-associated genetic variants have reduced progressively in human lineage

According to a study published in the Scientific Reports journal, the frequency of genetic variants linked to attention-deficit/hyperactivity disorder (ADHD) has reduced progressively in the evolutionary human lineage from the Palaeolithic to the present day.

29 May 2020

Study highlights crucial role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

28 May 2020

Gene associated with thinness may play a role in resisting weight gain

Some people can remain slim easily, irrespective of their diet, while others might be dieting and working out at the gym to maintain their shape.

25 May 2020

Genetic 'memory' of ancestral homelands helps organisms adapt to environmental change

Organisms carry long-term "memories" of their ancestral homelands that help them adapt to environmental change, according to a new study that involved raising chickens on the Tibetan Plateau and an adjacent lowland site.

22 May 2020

Gene mutation regulates plant responses to biotic stress

At times, scientists initiate their studies and find exactly what they had been looking for, while sometimes they end up with something unanticipated.

19 May 2020

Def gene essential for maintaining liver homeostasis and regeneration capacity

Hepatocytes are responsible for diverse metabolic activities in a liver. Proper ribosome biogenesis is essential to sustain the function of hepatocytes.

28 Apr 2020

Do Pancreatic Cells Write Their Own Autoimmune Ending?

Researchers have discovered that pancreatic cells, producing lipids, can create their own autoimmune ending. This article looks at how this is possible.

25 Mar 2020

New chromosome-level detectors developed to monitor cellular activity

For researchers investigating the regulatory processes in cells that are vital to all life, an innovative system that amplifies gene expression signals could be a turning point.

10 Mar 2020

Statistics used to find how genetics influence coffee intake

Some people feel like drinking three cups of coffee in a day while others feel content with just one cup, and some others give up entirely. Why is it so?

9 Mar 2020