Phenotype News and Research

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New Method Labels Viruses for Efficient Tracking and Tailoring

At the grocery store, barcodes make it quick and simple to identify products and frequently contain important details like quantity, location, and tracking.

22 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

Omicron's Cellular Senescence May Explain Cytokine Storms and Long-COVID

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

18 Dec 2023

Unveiling the Role of Exosomes in Regulating Hepatic Lipid Metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic lipids, is highly prevalent and can progress to cirrhosis and liver cancer.

12 Dec 2023

Study Sheds Light on Factors Contributing to Low-Level Viremia in HIV Patients

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

15 Nov 2023

Quantum Biology and AI Improve CRISPR Cas9 Efficiency in Microbes

Scientists at Oak Ridge National Laboratory used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

10 Nov 2023

Unlocking the Secrets of Memory: Key Protein Regulates Hippocampal Plasticity

Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.

3 Nov 2023

ISB Researchers Discover Genetic Key to T Cell Development

T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.

26 Oct 2023

Study Uncovers New Mechanism for Plant-Microbe Communication

Microorganisms that live on or in plant tissues form what is known as a plant microbiome. This interface plays an important role in plants' survival due to the existence of beneficial microorganisms.

19 Oct 2023

Study Uncovers Genes in Gut Microbe That Play Key Role in Early Colonization After Fecal Microbe Transplant

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants,

16 Oct 2023

Study Uncovers Novel Genes Linked to Coronary Artery Calcification

An international team of scientists has identified nearly a dozen genes that contribute to calcium buildup in our coronary arteries that can lead to life-threatening coronary artery disease, a condition responsible for up to one in four deaths in the United States.

12 Oct 2023

DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

New Halophyte Genome Sequence Sheds Light on Salt Tolerance Mechanisms

A Recent study conducted by Professor Qin Yuan's team from the Center for Genomics at the Haixia Institute of Science and Technology (Future Technology College) at Fujian Agriculture and Forestry University has been published in the prestigious journal Horticulture Research, which is a leading publication in the field of horticultural science.

25 Sep 2023

NC State Researchers Develop New Method to Produce Seedless Plants

North Carolina State University researchers have successfully transferred an important gene from one compartment of a plant cell to another to produce tobacco plants that lack pollen and viable seeds, while otherwise growing normally.

19 Sep 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Revealing a Novel Signaling Pathway Fostering Aging-Related Chronic Metabolic Disorders

Korean researchers have unveiled a novel signaling pathway that fosters aging-related chronic metabolic disorders.

4 Aug 2023

Study Offers Key Insights into the Structure of Neutral Mutations

An unexpected link between pure mathematics and genetics has been disclosed by an interdisciplinary group of mathematicians, physicists, engineers, and medical scientists. This helps disclose deep knowledge of the structure of neutral mutations and also the evolution of organisms.

2 Aug 2023

A Common Diabetes Drug Helps Prevent Muscle Atrophy and Muscular Fibrosis

You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis-;which can help the elderly bounce back faster from injury or illness.

26 Jul 2023