Pneumonia News and Research

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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.

Accurate diagnosis of bacterial superinfection pneumonia could help avoid antibiotic overuse

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

23 Aug 2021

International travelers may pick up AMR genes from different destinations

According to a research work published in the Genome Medicine journal, travelers abroad may contract bacteria and other vectors with genes that confer antibiotic resistance, which linger in the travelers’ gut when they return home.

9 Jun 2021

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

8 Jun 2021

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Researchers discover canine coronavirus in East Malaysia

Researchers have discovered a new coronavirus, found in a child with pneumonia in Malaysia in 2018, that appears to have jumped from dog to human.

21 May 2021

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Researchers have now identified how SARS viruses improve the production of viral proteins in infected cells such that new copies of the virus can be produced.

23 Apr 2021

Scientists generate a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

25 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

Human monoclonal antibodies can act as biological substitute for chemical antibiotics

In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice.

23 Feb 2021

Scientists identify new weapon to fight against antibiotic-resistant bacteria

As scientists around the globe wage war against a novel, deadly virus, one University of Colorado Boulder lab is working on new weapons to battle a different microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unchecked, could kill an estimated 10 million people annually by 2050.

24 Dec 2020

Gene expression database sheds light on pneumococcal infection

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).

16 Dec 2020

Researchers identify new therapeutic target to fight COVID-19 disease

In COVID-19 patients with severe lung disease, targeting the endothelial cells—that is, cells comprising the blood vessel wall, which control oxygen exchange between the bloodstream and airways—may be an innovative strategy to restore normal function of the lungs.

15 Dec 2020

Molecular markers in the blood can predict severe COVID-19 outcomes

Molecular markers in the blood shown to be predictive of severe COVID-19 outcomes resulting from SARS-CoV-2 coronavirus infection have been identified in a study by a Chinese research team.

15 Dec 2020

Study provides new insight on how lung bacteria protect against invading pathogens

New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal.

9 Dec 2020

Researchers determine role of NLRP1 protein in detecting the common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

From Nanyang Technological University Singapore (NTU Singapore) 3 Dec 2020

Research sheds light on T cell abnormality in critically ill COVID-19 patients

There is an idea within the coronavirus research field that there is some kind of T cell abnormality in critically ill COVID-19 patients, but specific details have not yet been clarified. To shed light on the problem, a research collaboration based in Kumamoto University (Japan) has performed a genetic analysis of T cells from lung tissue of COVID-19 patients.

23 Nov 2020

Pneumonia News and Research

Accurate diagnosis of bacterial superinfection pneumonia could help avoid antibiotic overuse

International travelers may pick up AMR genes from different destinations

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Researchers discover canine coronavirus in East Malaysia

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Scientists generate a detailed molecular atlas of lung development

Study shows how human viruses are better adapted to infect certain tissues

Human monoclonal antibodies can act as biological substitute for chemical antibiotics

Scientists identify new weapon to fight against antibiotic-resistant bacteria

Gene expression database sheds light on pneumococcal infection

Researchers identify new therapeutic target to fight COVID-19 disease

Molecular markers in the blood can predict severe COVID-19 outcomes

Study provides new insight on how lung bacteria protect against invading pathogens

Researchers determine role of NLRP1 protein in detecting the common cold virus

Research sheds light on T cell abnormality in critically ill COVID-19 patients

Researchers investigate solutions to make cell membranes resistant to coronavirus entry

Gaining new insights into bacterial pneumonia

New laboratory test can rapidly detect infectious agents in hospitalized patients

Rapid prognosis of SARS-CoV-2 by MALDI-TOF MS

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