Pneumonia News and Research

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Pneumonia is a leading cause of death and hospitalization, costing health care systems billions of dollars and an estimated 600,000 adult deaths worldwide each year. Pneumococcal disease is caused by the bacterium Streptococcus pneumoniae and the term describes a group of illnesses, including invasive infections, such as bacteremia/sepsis and meningitis, as well as pneumonia and upper respiratory tract infections. Although all age groups may be affected, the highest rate of pneumococcal disease occurs in young children and older adults. In addition, persons suffering from a wide range of chronic conditions (eg, diabetes, cardiovascular disease) and immune deficiencies are at increased risk.

Scientists develop lab-grown lung model to study SARS-CoV-2 infection

A team of Duke University researchers has developed a lab-grown living lung model that mimics the tiny air sacs of the lungs where coronavirus infection and serious lung damage take place. This advance has enabled them to watch the battle between the SARS-CoV-2 coronavirus and lung cells at the finest molecular scale.

23 Oct 2020

Researchers develop "mini lungs" to study SARS-CoV-2 infection

'Mini-lungs' grown from tissue donated to Cambridge hospitals has provided a team of scientists from South Korea and the UK with important insights into how COVID-19 damages the lungs.

23 Oct 2020

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

SARS-CoV-2 continues to cause an ongoing pandemic as of October 2020, with over 35 million reported cases and over 1 million deaths around the world.

13 Oct 2020

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Scientists have discovered a new cellular pathway that can be targeted with a naturally occurring medication to activate the regeneration of lung tissue.

30 Sep 2020

Researchers discover how antibiotic resistance genes spread via plasmids

For the first time, researchers have discovered how antibiotic resistance genes are spreading, at a continental scale, via bacterial plasmids in the hospital superbug, Klebsiella pneumoniae.

25 Sep 2020

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers have identified a druggable pocket in the SARS-CoV-2 Spike protein that could be utilized to prevent the virus from infecting human cells.

24 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Researchers identify an effective treatment for severe cases of COVID-19 infection

Scientists are trying to figure out how SARS-CoV-2 leads to a range of symptoms that appear to persist long after the active viral infection.

From Osaka University 1 Sep 2020

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Antibiotics are among the most important discoveries of modern medicine and have saved millions of lives since the discovery of penicillin almost 100 years ago.

25 Aug 2020

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

The human microbiota plays an important role in health and well-being by assisting in digestion, producing nutrients, resisting invading pathogens and regulating metabolism and the immune system.

25 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Synthetic peptide makes multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

7 Aug 2020

AI can be used as a supplementary tool for identifying causal pathogens of pneumonia

A team of researchers showed that artificial intelligence (AI) could help predict the type of bacteria that caused the infection in patients with pneumonia.

27 Jul 2020

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

20 Jul 2020

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.

15 Jul 2020

Researchers explore the reproduction of adenoviruses in cells

An adenovirus infection can be potentially life-threatening, especially for children after a stem cell transplant.

14 Jul 2020

Researchers evaluate role of zinc in COVID-19 prevention

Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.

14 Jul 2020

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

14 Jul 2020

Relationship between COVID-19 and food safety, biosecurity

The researchers, in this perspective, discuss about the recent outbreak of COVID-19 throughout the world and its relation with food safety and biosecurity.

25 Jun 2020

Potent human antibodies protect against SARS-CoV-2 in animal tests

A team led by Scripps Research has discovered antibodies in the blood of recovered COVID-19 patients that provide powerful protection against SARS-CoV-2, the coronavirus that causes the disease, when tested in animals and human cell cultures.

16 Jun 2020

Pneumonia News and Research

Scientists develop lab-grown lung model to study SARS-CoV-2 infection

Researchers develop "mini lungs" to study SARS-CoV-2 infection

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

Researchers identify specific cellular pathway involved in the regeneration of lung tissue

Researchers discover how antibiotic resistance genes spread via plasmids

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers review the role of macrophage activation syndrome in COVID-19

Researchers identify an effective treatment for severe cases of COVID-19 infection

Researchers describe new approach involving "antivitamins" to develop new antibiotics

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

Study may point to new therapeutic options for COVID-19

Synthetic peptide makes multidrug-resistant bacteria sensitive to antibiotics

AI can be used as a supplementary tool for identifying causal pathogens of pneumonia

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Researchers explore the reproduction of adenoviruses in cells

Researchers evaluate role of zinc in COVID-19 prevention

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Relationship between COVID-19 and food safety, biosecurity

Potent human antibodies protect against SARS-CoV-2 in animal tests

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