Protein Aggregation News and Research

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Innovative Technique Enables In Vivo Imaging of Intracellular Protein Aggregates

Tau aggregates have become the main study focus for figuring out the mechanisms underlying neurodegeneration since they are a prevalent form of amyloid protein. Tau fibrils and oligomers, among other forms of tau aggregates, have been linked to a variety of neurodegenerative disorders.

21 Jun 2023

Researchers Elucidate the Molecular Mechanism of Protein Degradation by Extracellular Chaperones

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

12 May 2023

Cold Temperature Increases Human Life Expectancy

Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging.

4 Apr 2023

Study identifies 238 amyloid toxicity protective or activator genes

An international study led by the Molecular Physiology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) identifies new genes that modulate the toxicity of the protein β-amyloid, responsible for causing Alzheimer's disease.

22 Mar 2023

Scientists unravel the physics of a cellular process linked to aggregation diseases

Researchers from Princeton University have uncovered the physics of a cellular process linked to aggregation diseases including Huntington's disease, paving the way to a deeper understanding of neurodegenerative disorders at the molecular level.

3 Feb 2023

European project promotes top-notch research in biochemistry and biophysics

TWIN2PIPSA, a new European project funded with €1.2 million, will support leading research and intensive training in the biochemistry and biophysics of protein folding, with implications and applications in biomedicine and biotechnology.

15 Nov 2022

Novel technique expedites research into the genetics of aging

A novel technique for identifying the genes that are important for aging has been discovered by scientists at North Carolina State University.

3 Nov 2022

Researchers get funding to develop a vaccine against ALS disease

DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.

8 Jul 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

Intermittent fasting slows aging and increases longevity in fruit flies, study shows

Whether intermittent fasting is called the 5:2 diet or the 16/8 method, celebrities swear that these eating regimens are a great way to lose weight. Fasting is now trendy, but real science backs up claims that fasting two days a week or restricting eating to an eight-hour window each day leads to weight loss.

30 Sep 2021

Bacteria-derived curli amyloid fibril promotes neurodegeneration in the host

Increasing evidence points to the fact that gut microbiota performs a vital role in regulating the advancement of neurodegenerative diseases like Alzheimer’s.

9 Sep 2021

Researchers develop a novel process to desalinate whey

Scientists reveal that the increased salt content of whey makes it one of the most polluting byproducts in the food processing industry.

7 Sep 2021

Nanobody mapping using NMR proves a promising alternative for therapeutic use

Researchers used NMR techniques to determine the structure of a nanobody, facilitating a better understanding of how the protein fights against diseases.

6 Jul 2021

First real-time observation of DNA-histone interactions

The genetic material of most organisms is carried by DNA, a complex organic molecule. DNA is very long -- for humans, the molecule is estimated to be about 2 m in length.

2 Jun 2021

Study: Sous vide cooking increases the digestibility of beef protein

Once used to prepare cuisine in only the finest restaurants, sous vide is now making its way into home chefs' kitchens. French for "under vacuum," the technique involves vacuum sealing food in a plastic pouch and then slowly cooking it in warm water.

10 Dec 2020

Plant amyloids could improve nutritional value of plant seeds, reduce allergenicity of legume seeds

Thanks to this work, as the journal Trends in Plant Science recently noted, it is now known that functional amyloids serve biological functions in representatives of almost all large groups of living organisms: bacteria, archaea, animals, fungi, and plants.

3 Dec 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Postnova Analytics' 2D FFF system opens up completely new ways for separations

Postnova Analytics powerful EAF4 technology combines the principle of Electrical and Asymmetrical Flow Field-Flow Fractionation in just one system.

From Postnova Analytics 17 Sep 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

Researchers identify osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020