Protein Folding News and Research

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The Surprising Impact of Chaperone Proteins on Multicellular Evolution

In a recent study, scientists used an instrument known as “experimental evolution” under the direction of researchers from the University of Helsinki and the Georgia Institute of Technology.

11 Mar 2024

New Insights Into How Cells Maintain Optimal Health

A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions (Zn2+) within our bodies. The discovery offers a deeper understanding of how our cells maintain optimal health.

4 Sep 2023

Researchers Uncover Astonishing Diversity of Protein Structures Previously Unexplored

The astounding variety of protein structures and their folds in nature has been further illuminated by a ground-breaking discovery. Researchers wanted to know how much of the huge range of potential protein structures nature had examined.

12 Jul 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Elaborating how amino acids shaped the genetic code of ancient microbes

Researchers discovered that without specific amino acids, ancient proteins would not have identified how to evolve into anything alive on the planet today, including plants, animals, and humans, by mimicking early Earth conditions in the lab.

28 Feb 2023

New method triggers and analyzes the dynamics of brain protein linked to Alzheimer’s

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

Structure of amyloid fibers formed by the protein hnRNPDL-2 determined

Using high-resolution cryo-electron microscopy (cryo-EM), UAB researchers determined the structure of amyloid fibers formed by the protein hnRNPDL-2, which has been linked to limb-girdle muscular dystrophy type 3 and concluded that the protein’s inability to form amyloid ﬁbers, rather than aggregation, would be the cause of the disease.

6 Feb 2023

New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

A figure from the paper depicts pathways perturbed in Alzheimer's disease. Below examples are listed for each pathway by major brain cell type. Image Credit: The Picower Institute.

4 Jan 2023

European project promotes top-notch research in biochemistry and biophysics

TWIN2PIPSA, a new European project funded with €1.2 million, will support leading research and intensive training in the biochemistry and biophysics of protein folding, with implications and applications in biomedicine and biotechnology.

15 Nov 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Researchers investigate the effects of transient oxygen starvation on protein folding in plants

Protein molecules require a defined shape in order to function. When they are created, their building blocks are therefore linked together in a very specific way.

13 Jul 2022

Stress helps remove the formation of toxic proteins in dementia

Recently, researchers have discovered a novel method that could help avoid the formation of protein tangles, which are typical in dementia.

12 May 2022

Study shows how optical and magnetic tweezers revolutionize thermodynamic research

The kinetic states of molecules have a vital role in the physiological and metabolic processes in which they participate in biophysics.

From University of Barcelona 24 Mar 2022

Future of AI in Life Science Research

In partnership with the SLAS 2022 exhibition and conference, we speak to Brian O’Sullivan about artificial intelligence and its future within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 1 Mar 2022

Stanford study reveals how ribosomes may contribute to age-related diseases

Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein folding.

20 Jan 2022

Research reveals how cancer cells thrive by exploiting genetic and cellular processes

Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited by cancer cells to promote tumor survival and growth.

From UC San Diego 27 Oct 2021