The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.
Scientists, for the first time, developed a successful method for pinpointing proteins within different kinds of neurons in the brain of a living animal.
Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.
Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.
Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.
The NIDCR has funded the creation of the Human Salivary Proteome Wiki, the first public platform that organizes information on each of the proteins found in human saliva.
A university has recently completed a study that suggests that the machinery responsible for handling the energy in fat tissues is performing poorly in obesity.
Researchers from Charité - Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes.
Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.
Swedish researchers have published novel molecular mapping of proteins that controls the process of cell division—detecting 300 of these proteins.
Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.
Cockroaches are notorious for their abilities to survive and reproduce, much to humanity's chagrin. In addition to scurrying around at night, feeding on human and pet food, and generating an offensive odor, the pests can transmit pathogens and cause allergic reactions.
Researchers at the University of Liverpool have unlocked new possibilities for the future development of sustainable, clean bioenergy.
Two decades after the release of the human genome, researchers have mapped the first-ever draft sequence of the human proteome.
The human body contains a vast number of proteins that are collectively called the proteome.
SARS-CoV-2 can lead to a broad range of symptoms, from absolutely nothing to multi-organ failure, severe respiratory stress, and eventually death.
Zika virus infection during pregnancy can cause severe abnormalities in the fetus, including malformations such as microcephaly. In a small proportion of cases, the disease may lead to miscarriage and perinatal death.
The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more.
A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, the State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Shanghai Jiao Tong University, recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide.
Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.
Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).