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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Exploring the Effects of Vascularization Strategies on Brain Organoids

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids' development.

18 Dec 2023

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Cryo-EM Analysis Uncovers Unexpected Enzymatic Switch in Bacterial Anti-Phage System

Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.

14 Dec 2023

CRISPR Takes Probiotics to the Next Level

Humans can benefit significantly from symbiotic relationships with probiotics-;live bacteria and microorganisms that influence the gut microbiota.

14 Dec 2023

Understudied Brain Cell Holds Key to Glioblastoma's Immunotherapy Resistance

Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years.

13 Dec 2023

Novel DNA Tension Probe Technology Offers Precise Measurement of Platelet Function

A novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods currently in use, an experimental study shows.

12 Dec 2023

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.

11 Dec 2023

Unraveling Oxygen's Impact on Protein Dynamics

Understanding the adverse effects of insufficient oxygen becomes apparent with the simple act of holding ones breath for too long.

11 Dec 2023

Zika's Enzyme Cascade Holds the Key to Viral Replication

Viruses operate with limited genetic material and a sparse protein repertoire, requiring efficient utilization of their components. The Zika virus serves as an illustrative case, producing only 10 proteins.

11 Dec 2023

New State-of-the-Art Genomic Services Facility Opening in the UK

Azenta Life Sciences has selected Oxford, UK, a key European life sciences hub, as the location for its next GENEWIZ Multiomics and Synthesis Solutions site.

From Azenta Life Sciences 8 Dec 2023

Unlocking the Mysteries of Fetal Brain Development

Cheryl Rosenfeld has dedicated three decades to investigating the transmission of biological information from mothers to babies during pregnancy.

6 Dec 2023

Blue Light Exposure Alters Cellular Processes Linked to Aging

In a study on fruit flies, daily low-intensity blue light exposure (BLE), similar to that experienced daily by billions of humans in the form of LED lighting and device screens, changed flies at the sub-cellular level, affecting processes related to aging and circadian rhythms.

6 Dec 2023

Brain Cell Genetics Drive Alzheimer's Progression

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

6 Dec 2023

Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

Revolutionizing Peptide Sequencing with Machine Learning for Personalized Medicine

Scientists are employing machine learning to examine the structure of unfamiliar cells, potentially opening the door to improved personalized medicine for addressing cancer and other serious ailments.

29 Nov 2023

The Extraordinary Genetic Memory System of Dormant Bacterial Spores

A recent investigation led by Professor Sigal Ben Yehuda and her team at Hebrew University has brought to light a fascinating aspect of bacterial dormancy.

28 Nov 2023

A Novel Technique for Ribonucleotide Quantification

Scientists at the Folkhälsan Research Center have devised a novel technique enabling the straightforward quantification of ribonucleotides in small tissue and cell samples within a standard laboratory setting, without the need for specialized equipment.

28 Nov 2023

FLSHclust Unveils 188 Novel CRISPR-Associated Gene Modules

Employing a groundbreaking algorithm named FLSHclust (“flash clust”), scientists have unearthed 188 uncommon and previously undiscovered CRISPR-associated gene modules, among billions of protein sequences. This includes the identification of a novel type VII CRISPR-Cas system.

24 Nov 2023

Unraveling the Molecular Basis of SIDT1 and SIDT2 in C. elegans

New work thoroughly characterizes the structural features of human SIDT1 and SIDT2, revealing their existence as dimers in vitro and their tendency to form dimers or higher-order oligomers in their natural environment.

23 Nov 2023

New Method Removes Background Noise from CITE-Seq Data

Researchers from the Chobanian & Avedisian School of Medicine and the College of Arts & Sciences at Boston University have devised an innovative tool to address this limitation. This tool can discern and eliminate undesirable background noise originating from various sources, enhancing the precision of analysis in CITE-seq experiments.

20 Nov 2023