Schizophrenia News and Research

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Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Combined effect of rare mutations has negative impact on health and longevity

In a study published recently in the eLife journal, researchers have reported that the combined effects of rare and damaging mutations that occur at birth itself have adverse effects on health span and longevity.

13 Apr 2020

Study shows some genetic variants have stronger effects on RNA expression even before birth

The prefrontal cortex of the human brain experiences a wider spectrum of developmental activity right from early prenatal development until childhood.

8 Apr 2020

Study unveils genetic variants that play key role in psychiatric, neurological conditions

The cerebral cortex is important for memory, thinking, attention, and information processing. It is an outer, folded, and comparatively thin “gray matter” layer of the brain.

27 Mar 2020

Regulating ion flow using a ball-and-chain mechanism

Ion channels that permit potassium and sodium ions to move in and out of cells are essential for the function of the brain and heart, and also for neuronal “firing” in the central nervous system.

19 Mar 2020

Study finds impact of specific gene on neurodevelopment, causing ASD and macrocephaly

During the developmental phase of brains, a number of moving parts occur—and if mutations occur during the early neurodevelopment, it can result in disorders such as autism and macrocephaly.

12 Mar 2020

Distinct loss-of-function variants cause shared clinical features in neuronal development disorders

Researchers have shown that mutations in four distinct genes that lead to Kleefstra syndrome.

20 Feb 2020

Understanding bipolar disorder and its potential future developments

Bipolar disorder is estimated to affect around 1 to 4% of the population, but understanding the underlying genetics has proved a major challenge.

15 Feb 2020

Schizophrenia News and Research

Combined effect of rare mutations has negative impact on health and longevity

Study shows some genetic variants have stronger effects on RNA expression even before birth

Study unveils genetic variants that play key role in psychiatric, neurological conditions

Regulating ion flow using a ball-and-chain mechanism

Study finds impact of specific gene on neurodevelopment, causing ASD and macrocephaly

Distinct loss-of-function variants cause shared clinical features in neuronal development disorders

Understanding bipolar disorder and its potential future developments

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