An epileptic seizure, occasionally referred to as a fit, is defined as a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain".
A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.
The largest genetic study of its kind, coordinated by the International League Against Epilepsy, including scientists from FutureNeuro at RCSI University of Medicine and Health Sciences, has discovered specific changes in our DNA that increase the risk of developing epilepsy.
Specific alterations in human DNA have been shown to raise the likelihood of getting epilepsy, according to the biggest genetic study of its type, which was managed by the International League Against Epilepsy and involved researchers from FutureNeuro at RCSI University of Medicine and Health Sciences.
In people with epilepsy, seizure-alert dogs can smell small changes in body chemistry and warn of an impending seizure an hour or more before it occurs.
Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.
Biologists at the University of Iowa have conclusively connected epilepsy with the brain’s immune system.
Glioma is one of the most aggressive malignant primary brain tumors. A common feature of glioma is the presence of localized, intermittent seizures referred to as glioma-related epilepsy, which is known to promote tumor growth. However, the mechanism involved at the molecular level is still not clear.
Children’s Hospital of Philadelphia (CHOP) researchers have identified a particular genetic variant in SCN1A, the most common genetic epilepsy, that contributes to an earlier start of epilepsy with clinical features different from other epilepsies.
Which organisms survive and which succumb when the climate changes? A small larval fish is providing surprising insight into how the brain reacts when the temperature rises.
According to a study headed by researchers from USC Stem Cell and the USC Neurorestoration Center, adults may recover at least some of what they have lost by producing new brain cells, and this process is profoundly modified in patients with long-term epilepsy.
A team led by scientists at the University of Washington and special agents with the U.S. Department of Homeland Security has used genetic testing of ivory shipments seized by law enforcement to uncover the international criminal networks behind ivory trafficking out of Africa.
Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.
Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.
An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment.
Epilepsy, results from impairment in brain cells and is often treated with drugs that counteract or control the seizures.
Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.
Studies show that a pair of mutations detected in people with developmental and epileptic brain disease can be traced back to the same ion channel.
Brain function depends on inhibitory cells that balance or 'brake' excitation. These neurons allow the brain to process information and also prevent runaway seizures.
When two scientists from NIST brought black lights and glow powder into the crime lab, they were not setting up a laser tag studio or nightclub.