Tau proteins are microtubule-associated proteins found in neurons in the brain.
The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?
Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.
According to a recent research, enhancing the expression of one gene in cells that help the brain’s neurons, shields neurons in mouse models of Alzheimer’s disease.
Scientists from the Icahn School of Medicine at Mount Sinai published the first of its kind research in the field of addiction genetics employing a multi-omics method to offer a huge list of causal candidate genes linked with alcohol consumption and alcohol use disorder (AUD).
Scientists have found that a particular chemical feature of a crucial protein may cause it to build up in the brain and lead to various disorders.
Studies conducted on patients’ tissue as well as mini-brains created from stem cells have provided a better insight into Alzheimer’s disease.
A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.
Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.
A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.