Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.
RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.
Scientists from the University of Southampton have identified a novel means to create human cartilage tissue from stem cells.
Depending on how it occurs, the development of cellular agriculture -; food grown in factories from cells or yeast -; has the potential to either accelerate socioeconomic inequality or provide beneficial alternatives to the status quo.
A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells.
Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.
Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.
Despite our efforts to sort and recycle, less than 9% of plastic gets recycled in the U.S., and most ends up in landfill or the environment.
A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.
In research that may eventually help crops survive drought, scientists at Princeton University have uncovered a key reason that mixing material called hydrogels with soil has sometimes proven disappointing for farmers.
The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.
Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience.
Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall.
Fibrous proteins such as collagen and fibrinogen form a thin solid layer on the surface of an aqueous solution similar to the "skin" that forms on warm milk, according to a team of Penn State Researchers, who believe this finding could lead to more efficient bioprinting and tissue engineering.
News-Medical talks to Dr. Mo Ebrahimkhani about his research using genetic engineering together with a machine-learning algorithm to mature a lab-grown 'designer liver organoid'.
Finding just the right model to study human development--from the early embryonic stage onward--has been a challenge for scientists over the last decade.
Organoids are stem cell-based tissue surrogates that can mimic the structure and function of organs, and they have become a key component of numerous types of medical research in recent years.
In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.
When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.
In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.