Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
Researchers from Monash University’s Engineering Department have achieved a significant breakthrough by using “bioinks” that include living nerve cells (neurons) to 3D print nerve networks.
A research team, affiliated with UNIST has achieved a groundbreaking milestone in tissue regeneration by developing a technology that utilizes autologous blood to produce three-dimensional microvascular implants.
Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.
The 3B’s Research Group at the University of Minho, Portugal, is using microfluidics technologies from Dolomite Microfluidics to create complex hydrogel structures that can mimic biological microenvironments.
Scientists from the NIHR Great Ormond Street Hospital Biomedical Research Centre (a collaboration between GOSH and UCL), London, and University of Padova, Italy, have shown for the first time how 3D printing can be achieved inside 'mini-organs' growing in hydrogels -- controlling their shape, activity, and even forcing tissue to grow into 'molds.'
Printing living cells into functional tissues is a highly complex process, and with each technological advancement, new challenges emerge. The Levato lab at UMC Utrecht has successfully combined two promising printing processes to boost cell density, cell survival, and specialization in bioprints. The solution: granular biogels or resins.
The National University of Singapore (NUS) research team has successfully 3D-printed an edible cell culture scaffold using common plant proteins, allowing for more inexpensive and sustainable lab-grown meat to be served on the table.
Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.
Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.
Let's say you needed to move an individual cell from one place to another. How would you do it? Maybe some special tweezers? A really tiny shovel?
Maintenance of sulfomucin is a key end point in the treatment of diarrhea and inflammatory bowel disease (IBD). However, the mechanism underlying the microbial sense to sulfomucin are poorly understood, and to date, there are no therapies targeting the secretion and maturation of sulfomucin in IBD. Considering the important role of gut microbiota in host immune regulation, maintain sulfomucin by modulating the gut microbiota is inspired.
Building tissues and organs is one of the most complex and important tasks that cells must accomplish during embryogenesis.
Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between.
The National Institute of Biomedical Imaging and Bioengineering awarded Case Western Reserve $6.1 million to develop body tissue engineering.
New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.
Heart disease -; the leading cause of death in the U.S. -; is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.
Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide.
Professor Qiuyu Zhang (Northwestern Polytechnical University), Professor Ki-Bum Lee (Rutgers University), and Professor Liang Kong (School of Stomatology, The Fourth Military Medical University) directed this research.
Researchers have used sound waves to turn stem cells into bone cells, in a tissue engineering advance that could one day help patients regrow bone lost to cancer or degenerative disease.
In this interview, we speak to Dr. Y. Shrike Zhang about his latest bioprinting technique that allows tissues to be preserved for later use.