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Small Genetic Element Identified as Key to Potato Industry's Production Problem

Researchers have discovered a game changer for the potato industry.

12 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

Scientists Predict DNA Mutations Causing Extra Fingers, Hearts

Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.

7 Feb 2024

New Insights Into How Genetic Variation Affects Gene Expression

Chromatin accessibility and transcription factor binding are determined by genetic variation, according to a recent study from the University of Eastern Finland.

23 Jan 2024

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Decoding Zebrafish Development: A Comprehensive Gene Expression Atlas

Scientists from the National Institutes of Health have released a comprehensive guide to the development of zebrafish, outlining the gene expression patterns activated in almost every cell type during the initial five days of growth.

19 Dec 2023

Unraveling Oxygen's Impact on Protein Dynamics

Understanding the adverse effects of insufficient oxygen becomes apparent with the simple act of holding ones breath for too long.

11 Dec 2023

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

The Dominant Phage-Resistant LAB in Long-Term Kimchi Fermentation

Scientists from the World Institute of Kimchi have successfully extracted lactic acid bacteria (LAB) strains that exhibit remarkable phage resistance.

2 Nov 2023

New Computational Approach Efficiently Identifies Optimal Genetic Perturbations

A strategy for cellular reprogramming involves using targeted genetic interventions to engineer a cell into a new state.

3 Oct 2023

New Halophyte Genome Sequence Sheds Light on Salt Tolerance Mechanisms

A Recent study conducted by Professor Qin Yuan's team from the Center for Genomics at the Haixia Institute of Science and Technology (Future Technology College) at Fujian Agriculture and Forestry University has been published in the prestigious journal Horticulture Research, which is a leading publication in the field of horticultural science.

25 Sep 2023

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job.

25 Aug 2023

Researchers Lead Innovative Studies on Mammalian Aging and Life Span

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

11 Aug 2023

New Insights Into How T Cells Become Exhausted in Cancer

Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.

7 Aug 2023

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

The Mechanism of Immune Memory Development

The memory of the immune system depends on distinctive epigenetic traits and a particular 3D arrangement of the DNA in the nucleus of memory cells, allowing for rapid activation of these cells, according to a team of researchers from the Erasmus University Medical Center, the Centre for Genomic Regulation (CRG), and the Josep Carreras Leukaemia Research Institute.

12 Jul 2023

New Insights Into How Genes Are Activated

Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can't access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.

12 Jul 2023

Negative Modulation of Arabidopsis Salinity Tolerance by CONSTANS Protein

Arabidopsis (Arabidopsis thaliana)’s photoperiodically controlled flowering and circadian pathways are primarily regulated by CONSTANS (CO), a well-known B-box family member.

5 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023