Triple Negative Breast Cancer News and Research

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U of T Scientists Make Breakthrough Discovery in DNA Repair Mechanism

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

18 Apr 2024

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Researchers identify key molecular differences between initial and metastatic tumors

Researchers at Johns Hopkins Medicine claim to have discovered significant molecular variations between cancer cells that adhere to an initial tumor and those that spread out to develop distant tumors while researching the fatal form of breast cancer known as triple negative.

9 Aug 2022

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

New treatment developed from plant virus could keep metastatic cancers at bay

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.

From UC San Diego 15 Sep 2021

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021

Triple Negative Breast Cancer News and Research

U of T Scientists Make Breakthrough Discovery in DNA Repair Mechanism

Immune Evasion Mechanism of TNBC Cells Discovered

Researchers identify key molecular differences between initial and metastatic tumors

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

New treatment developed from plant virus could keep metastatic cancers at bay

Study: Biomarker can predict response to immunotherapies in breast cancer patients

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Chromosomal instability is associated with cancer's aggressiveness

Triple-negative breast cancer's ecosystem reveals potential therapeutic targets

Novel nano drug candidate kills triple negative breast cancer cells

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

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