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Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

A cryptic molecule can awaken killer viruses from their slumber

Some gut bacteria have a spooky superpower: they can reanimate dormant viruses lurking within other microbes.

24 Feb 2022

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

The prognosis for ovarian cancer patients is grim: less than half of high-grade serous ovarian cancer (HGSC) patients survive past five years from diagnosis. Initially, the tumors typically respond well to chemotherapy but become resistant after repeated treatments, enabling the cancer to regrow.

24 Feb 2022

Study decodes the heterogeneity of tumor-infiltrating immune cell composition in diffuse large B-cell lymphoma

In Finland, about 700 people are identified with diffuse large B-cell lymphoma (DLBCL) every year.

24 Feb 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Key regulator of cell differentiation discovered

Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body.

22 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

Researchers discover dysregulation of transfer RNA expression in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

Our immune systems have the potential to find and destroy cancer cells. But cancer cells can be clever and develop tricks to evade the immune system.

17 Feb 2022

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Joint study will assess clinical value of comprehensive genomic profiling (CGP) on cancer therapy options in patients with advanced disease

17 Feb 2022

Plant-based nanoparticles likely to provide anti-cancer drug

Nanomaterials have transformed cancer therapy, and plant-derived nanoparticles have the added benefit of being cost-effective and simple to produce in mass.

From Tokyo University of Science 16 Feb 2022

New study calls for the need of additional immunogenetic research in diverse populations

Humans and their pathogens interact in a complex way, resulting in disease and health.

16 Feb 2022

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Lung cancer is the second leading cancer in the United States and the No. 1 cause of cancer-associated deaths.

15 Feb 2022

Immune cells leave traces on metastasis in the brain, likely to help future treatments

Researchers from the University of California San Francisco discovered two functional archetypes of metastatic cells spanning seven different types of brain cancers.

14 Feb 2022

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Antibody-drug conjugates, an intricate that covalently links a potent cytotoxin to an antibody, have piqued the interest of researchers as a new bio-therapeutic methodology.

14 Feb 2022

Researchers develop a method for preserving human primordial germ cell-like cells

Human primordial germ cells (PGCs) are the early precursors of the eggs (oocytes) and sperm that are necessary to keep humankind alive and reproducing.

11 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

In vivo tracking of unlabeled stem cells using sugars

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers -; made out of sugars -; that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Tumor News and Research

Chlamydia and HPV co-infection causes a unique cellular reprogramming, study shows

A cryptic molecule can awaken killer viruses from their slumber

Study identifies a new cancer cell state related to poor treatment response in ovarian cancer patients

Study decodes the heterogeneity of tumor-infiltrating immune cell composition in diffuse large B-cell lymphoma

Recent study reveals the code involved in human gene regulation

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

Key regulator of cell differentiation discovered

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

Researchers discover dysregulation of transfer RNA expression in cancer

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Plant-based nanoparticles likely to provide anti-cancer drug

New study calls for the need of additional immunogenetic research in diverse populations

Cancer driving protein plays crucial role in the development of lung cancer, study reveals

Immune cells leave traces on metastasis in the brain, likely to help future treatments

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Researchers develop a method for preserving human primordial germ cell-like cells

Kras oncogenes use genetic reprogramming to drive tumorigenesis

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

In vivo tracking of unlabeled stem cells using sugars

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