Vaccine News and Research

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A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so that the immune system can more easily recognize and destroy any of these microorganisms that it later encounters.

“Free-from-Tree” Production of Vaccine Component QS-21

For the first time, a valuable chemical extracted from the soapbark tree and utilized as a major component in vaccinations has been duplicated in a different plant host, providing the vaccine industry with hitherto unheard-of potential.

29 Jan 2024

New Method Labels Viruses for Efficient Tracking and Tailoring

At the grocery store, barcodes make it quick and simple to identify products and frequently contain important details like quantity, location, and tracking.

22 Jan 2024

LJI Researchers Identify Late-Rising T Cells Crucial for CMV Control

Cytomegalovirus (CMV) is a pathogen that likes to lurk. Most adults already carry CMV, and they show no symptoms at all.

22 Jan 2024

McMaster Team Publishes Instruction Manual for Detecting Rare B Cells

Researchers with McMaster University have created the instruction manual that will help scientists across the globe find hard to detect B cells.

22 Jan 2024

Glowing COVID-19 Diagnostic Test Prototype Produces Results in One Minute

Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical?

19 Jan 2024

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body.

5 Dec 2023

Breakthrough Research in Leishmaniasis Reveals Pain-Suppression Pathways

For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

1 Dec 2023

Structural Insights Into Coronavirus Spike Proteins

Coronaviruses employ protein “spikes” to latch onto and infect cells. Contrary to their name, these spikes do not have a rigid and pointed structure. Instead, they resemble chicken drumsticks, with the meaty portion facing outward.

27 Nov 2023

Gene-Edited Chickens in Fight Against Bird Flu

Scientists have used gene editing techniques to identify and change parts of chicken DNA that could limit the spread of the bird flu virus in the animals.

11 Oct 2023

Pure Capped mRNA Vaccine Opens the Door to More Effective Vaccines with Lower Chances of Inflammation

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

11 Oct 2023

LJI Scientists Harness 'Helper' T Cells To Treat Tumors

Scientists are on the hunt for a unique set of mutations, called "neoantigens," that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to neoantigens and target tumor cells for destruction.

4 Sep 2023

Analyzing the First Vaccine Against Respiratory Syncytial Virus in Many Older Adults

The first Americans over age 60 just started rolling up their sleeves to get vaccinated against respiratory syncytial virus, or RSV, now that brand-new vaccines have started to arrive at pharmacies and clinics.

23 Aug 2023

Viral Proteins Promote the Spread of Protein Aggregates in the Brain

Viral genetic remnants found naturally in the human genome may influence the development of neurodegenerative diseases.

22 Aug 2023

SARS-CoV-2 Infection is Significantly Linked With the Development of High Blood Pressure

An analysis of electronic medical records for more than 45,000 people found that COVID-19 infection was significantly associated with the development of high blood pressure, according to new research published today in Hypertension, an American Heart Association journal.

22 Aug 2023

Study Finds Diverse Set of Immune Cells Linked to Flu Protection

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

AI Tool Speeds Up Vaccine Development

From tackling homework challenges to drafting emails, people are discovering a vast array of applications for natural language processing tools like generative artificial intelligence (AI) engines.

14 Aug 2023

Persons With Type 2 Diabetes are More Likely to Experience Changes in Brain Structure

The longer a person has type 2 diabetes, the more likely they may be to experience changes in brain structure, a Michigan Medicine study finds.

11 Aug 2023

Study Links Adenovirus Infection With a Rare Blood Clotting Disorder

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

11 Aug 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023