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New gel enhances immunotherapy's effectiveness in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues.

7 Oct 2021

Researchers reveal how and why cytoquakes occur

Researchers earlier identified that animal cell cytoskeletons rearrange quickly at times, starting an earthquake-like disturbance in the part of the cell.

7 Oct 2021

Researchers develop novel antibacterial nanomaterial to treat skin infections

Researchers at the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Technical University of Liberec in collaboration with researchers from the Institute of Microbiology of the CAS, the Department of Burns Medicine of the Third Faculty of Medicine at Charles University (Czech Republic), and P. J. Šafárik University in Košice (Slovakia) have developed a novel antibacterial material combining nonwoven nanotextile and unique compounds with antibacterial properties.

1 Oct 2021

Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Scientists find two proteins that pair up to build lifelines to cancer cells

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

21 Sep 2021

New Cornell study finds potential treatment for MRSA ‘superbug’

A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.

17 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

New collaboration to support start-up companies in regenerative medicine space

A new collaboration has been forged by Phase Holographic Imaging by offering its technology to support start-up companies in the regenerative medicine space.

4 Aug 2021

Stiffness of protein fibers plays a key role in controlling cell movement, study shows

A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells.

23 Jul 2021

Cell couriers offer clue to how cancers metastasize into secondary tumors

A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University of Warwick.

From The University of Warwick 22 Jul 2021

Study holds phages responsible for superbug emergence

Scientists unraveled that phages are responsible for the initiation of rapid bacterial evolution that leads to the rise of treatment-resistant “superbugs.”

From University of Pittsburgh 21 Jul 2021

Researchers from Himachal Report a Novel Bacterial Biopigment with Diverse Applications

Researchers have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

9 Jul 2021

Protein's 'silent code' influences cell movement

The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly identical, sharing 99% of their amino acid sequence.

8 Jul 2021

Study shows how scar tissue can effectively regenerate the injured heart

It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a new study, researchers from the University of Tsukuba have shown how cells in the scar tissue can be converted to heart muscle cells, effectively regenerating the injured heart.

3 Jun 2021

Cancer cells re-organize DNA structure to ramp up the activity of oncogenes

A lot of biological mechanisms go wrong in cancer—for example genes mutate and cells proliferate in an uncontrollable manner.

11 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Macrophages perform necessary damage-control function following tissue injury

Cardiovascular disease, the most common cause of death, is the result of oxygen deprivation as blood perfusion to affected tissue is prevented. To halt the development of the disease and to promote healing, re-establishment of blood flow is crucial.

26 Apr 2021

POSTECH researchers bioengineer a novel drug-delivering adhesive patch platform

Blood vessels deliver nutrients and oxygen to each organ in our body. They are difficult to completely restore to their original conditions once damaged by myocardial infarction or severe ischemic diseases. This is because various angiogenic growth factors must be applied sequentially in order to restore the vascular structure.

13 Apr 2021

New stem cell therapy shows promise to help patients with non-healing diabetic foot ulcers

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

8 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021