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Tweezers illustrate how chemotherapy affects DNA

A recent study from Cornell University offers a new perspective on how the chemotherapy agent etoposide delays and kills vital enzymes that support the growth of cancer cells.

31 Jan 2023

AI-based strategy helps discover high-affinity antibody drugs

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

31 Jan 2023

Study suggests new strategies for controlling plant biochemistry

Plant biochemists at the U.S. Department of Energy's Brookhaven National Laboratory have discovered a new level of regulation in the biochemical "machinery" that plants use to convert organic carbon derived from photosynthesis into a range of ring-shaped aromatic molecules.

12 Jan 2023

Effective anticancer strategy for selective killing of cancer cells

A study team headed by Dr Yuanliang Zhai from The University of Hong Kong’s (HKU) School of Biological Sciences and his associates from The Hong Kong University of Science and Technology (HKUST) and Institut Curie in France discovered a new mechanism of the human MCM2-7 complex in controlling replication initiation, which can be employed as a unique and effective anticancer method with the potential for selective death of cancer cells.

11 Jan 2023

Analyzing the success rate of cell-cell metabolite exchange

It is said that when there is an exchange of metabolic products of the cells with other cells, their lifespan gets longer. This discovery has been given by a research group at Charité – Universitätsmedizin Berlin, which made the breakthrough in a study with the help of yeast cells.

11 Jan 2023

Novel insights into the elongation dynamics of eukaryotic cells

The proper functioning of numerous proteins generated in cells by ribosomes is essential for life. This diversified variety of proteins, called proteome, is sustained by the ribosomes’ vigorous translation elongation of amino acid sequences.

6 Jan 2023

Elucidation of mitochondrial membrane pore formation

Human metabolism depends on mitochondria, which are regarded as the power plants of cells. But since 40% of the proteins in the mitochondria are dysfunctional and are linked to human diseases, mitochondria also play a significant role in medical research.

6 Jan 2023

AI creates artificial DNA to control cell protein production

Researchers at Chalmers University of Technology in Sweden have developed synthetic DNA that uses artificial intelligence to control the production of proteins in cells.

25 Nov 2022

Researchers discover murderous survival strategy of yeast

Yeast is not the simple single-celled microorganism we once thought, but a competitive killer. When starved of glucose, yeast releases a toxin that will poison other microorganisms that have entered its surrounding habitat, even its own clones.

8 Nov 2022

Regulating cholesterol production with novel protein

Everyone must have heard about cholesterol and how important it is to eat heart-healthy meals to keep it under control.

From The University of New South Wales (UNSW) 8 Nov 2022

Gene editing technique makes new kinds of research possible in animal models

Working in teeny tiny worms, scientists can now test the effects of thousands of genetic mutations in one fell swoop.

3 Nov 2022

New technique could help fine-tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

2 Nov 2022

Understanding the architectures of proteins and the machinery at genes

Researchers from Cornell University have discovered a crucial mechanism in how genes are controlled thanks to yeast, a small organism that is necessary for the production of beer and bread.

1 Nov 2022

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Meiotic drive systems can be maintained for long evolutionary timespans

Meiotic drivers, which are a sort of selfish gene, are, in fact, selfish. They are found in nearly all species’ genomes, including humans, and unfairly convey their genetic information to more than half of their offspring, resulting in infertility and impaired organism health.

21 Oct 2022

Building designer plant cuticles with important protective functions

Scientists are working to bioengineer a common defense mechanism that most plants develop naturally to protect against drought, insects and other environmental stresses.

11 Oct 2022

Making synthetic biology applications feasible using RNA origami

Synthetic biology aims to acquire comprehensive control over biological functions to produce designer organisms for a range of commercial, diagnostic, and therapeutic uses.

6 Oct 2022

Coral genome reveals cysteine biosynthesis pathways

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

26 Sep 2022

New imaging technologies to evade immune responses of Candida albicans

Researchers from the Monash Biomedicine Discovery Institute have demonstrated how the common fungus Candida albicans evades immune responses using newly discovered imaging technologies. The researchers claim that this involves a fungus that can shape-shift in an “alien-like” manner to escape immune cells.

21 Sep 2022

Researchers analyze how clusters of molecules meet inside cells

A developing area studies how clusters of molecules gather inside of cells, similar to how oil droplets form and separate from the water in a vinaigrette.

From New York University (NYU) 15 Sep 2022