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Fission Yeast Analysis Reveals Two Key Genes Involved in Gross Chromosomal Rearrangement

When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in the body.

26 May 2023

From Clocks to Cells: Unleashing the Potential of Dual Oscillatory Signaling

Christian Huygens recorded his observations of the synchronization of two pendulum clocks in 1665. It takes precise quantitative control to properly regulate oscillatory dynamics, which are seen in essential biological processes including circadian clocks, segmentation, and transcription factor responses in addition to physical systems.

22 May 2023

Infections with the Fungus Candida auris on the Rise in Germany

Candida auris is an extremely new species among yeasts from the Candida genus that cause infections in humans: it was only reported in 2009, and no evidence has been found prior to the 1990s.

16 May 2023

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.

15 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

How the Natural Process of DNA Repair Fails to Cause Disease

We often come to an understanding of what causes a disease. We know, for example, that cancers are caused by mutations at critical locations in the genome, resulting in loss of control of cell growth.

11 May 2023

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Researchers at the Department of Biology, University of Copenhagen, have now contributed to solving this problem for a specific gene called GCK. The study has just been published in Genome Biology.

4 May 2023

Reprogramming the Aging Process to Effectively Promote Longevity

Human lifespan is associated with the aging of individual cells. Three years ago, a group of researchers from the University of California, San Diego, uncovered fundamental mechanisms underlying the aging process.

28 Apr 2023

Using Synthetic Biology to Reprogram the Cellular Aging Process in Yeast

Engineering a synthetic oscillator that cycles between the two deterioration pathways that lead to cell death can slow aging in yeast cells, increasing their longevity by more than 80%, a new study reports.

28 Apr 2023

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Biosensors-;sensors that can detect biological samples-;are powerful tools for understanding the function, composition, and structure of biochemical molecules.

26 Apr 2023

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Artificially synthesizing genomes has numerous applications, including medical research and industrial strains. Scientists are continuously progressing in the depth and breadth of genome design and synthesis, from Craig Venter’s team’s synthesis of the artificial life JCVI-syn1.0 in 2010 to the rewriting and synthesis of the prokaryotic E. coli genome, and the Sc2.0 project’s artificial synthesis of the yeast genome.

26 Apr 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

A Previously Unknown Mechanism for DNA Folding Revealed

A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics.

20 Apr 2023

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs.

7 Apr 2023

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress.

7 Apr 2023

Using Purified Curcumin to Create Probiotic Yogurt that Contains No Artificial Preservatives

Researchers have succeeded for the first time in adding a highly purified form of curcumin to yogurt in a way that ensures it remains dissolved in the dairy product and preserves it, while tasting good.

4 Apr 2023

Machine learning reveals the complexities of difficulties in designer chromosome synthesis

Artificially synthesizing genomes has several applications, including medical research and industrial strains.

28 Mar 2023

Study identifies 238 amyloid toxicity protective or activator genes

An international study led by the Molecular Physiology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) identifies new genes that modulate the toxicity of the protein β-amyloid, responsible for causing Alzheimer's disease.

22 Mar 2023

Gene that regulates cadmium distribution between leaf and grain in rice

Due to its accumulation in crops, specifically rice, cadmium (Cd), a hazardous heavy metal contaminant of cultivated land, poses a threat to human health. Thus, it is vital to develop methods to prevent Cd from accumulating in rice grains.

14 Mar 2023

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Microorganisms live in or on almost every part of the human body and play an important role in the regulation of normal human processes. As a result, changes in the number or type of microorganisms, also known as the microbiome, can contribute to disease and altered responses to therapy, including cancer treatment.

14 Mar 2023

Yeast News and Research

Fission Yeast Analysis Reveals Two Key Genes Involved in Gross Chromosomal Rearrangement

From Clocks to Cells: Unleashing the Potential of Dual Oscillatory Signaling

Infections with the Fungus Candida auris on the Rise in Germany

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How the Natural Process of DNA Repair Fails to Cause Disease

Researchers Map GCK Gene Variants to Better Diagnose Hereditary Diseases

Reprogramming the Aging Process to Effectively Promote Longevity

Using Synthetic Biology to Reprogram the Cellular Aging Process in Yeast

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Interpretable Machine Learning Framework Helps Optimize Chromosome Design and Synthesis

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

A Previously Unknown Mechanism for DNA Folding Revealed

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Key Enzyme in Sugar Metabolism Plays Role in Protecting Cancer Cells

Using Purified Curcumin to Create Probiotic Yogurt that Contains No Artificial Preservatives

Machine learning reveals the complexities of difficulties in designer chromosome synthesis

Study identifies 238 amyloid toxicity protective or activator genes

Gene that regulates cadmium distribution between leaf and grain in rice

Understanding the relationship between gut microbiome and CAR T-cell therapy response

CITES: Regulating the International Wildlife Trade to Preserve the Viability of Species

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

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