in vivo News and Research

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Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Researchers at Pompeu Fabra University have shown for the first time that blood vessels communicate with neurons in the peripheral nervous system, regulating their proliferation and differentiation.

17 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

New study can help treat metabolic and genetic bone diseases

A team of researchers, headed by Kanazawa University, has demonstrated that a tiny fish can potentially stop painful genetic and metabolic bone diseases. The study was recently published in the Communications Biology journal.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Type 1 diabetes mellitus and type 2 diabetes mellitus (T2DM) are the two main types of diabetes, while T2DM accounts for 90%-95% of those with diabetes.

14 Jul 2020

Bird poop may pose more health risks than people realize, shows study

Bird poop may pose more health risks than people realize, according to Rice University environmental engineers who study antibiotic resistance.

14 Jul 2020

New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Metagenomic data on intestinal microflora can open up treatments for intestinal dysbiosis

Scientists from Osaka City University, The Institute for Medical Science, and The University of Tokyo have presented intestinal viral and bacterial metagenome data from the fecal samples collected from 101 healthy Japanese persons.

13 Jul 2020

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

From University of Alabama 10 Jul 2020

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

10 Jul 2020

Researchers design novel enzyme to study the interactions between proteins

Proteins regulate several physiological functions that are crucial for living things in vivo. More than 20,000 protein types are found in human beings.

7 Jul 2020

Researchers identify protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

6 Jul 2020

Novel technology significantly improves the quality of stem cells

For years, stem cells have continued to have excellent potential in regenerative medicine.

6 Jul 2020

Researchers discover protein involved in protecting B cells

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, which produce antibodies that target and neutralize pathogens.

2 Jul 2020

Mouse models help understand the functioning of muscles

The quest to detect all kinds of proteins that constitute the sarcomere, the fundamental contractile unit of muscle cells, led to a surprising revelation.

22 Jun 2020

Fantastic Muscle Proteins And Where To Find Them

Researchers at MDC developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract.

22 Jun 2020

Inhibitory interneurons excite the developing brain, study finds

Brain function depends on inhibitory cells that balance or 'brake' excitation. These neurons allow the brain to process information and also prevent runaway seizures.

15 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

in vivo News and Research

Modified mRNAs improve efficiency of protein synthesis

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

New study can help treat metabolic and genetic bone diseases

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Bird poop may pose more health risks than people realize, shows study

New technology generates immune response by delivering antigens to APCs in the spleen

Metagenomic data on intestinal microflora can open up treatments for intestinal dysbiosis

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Researchers design novel enzyme to study the interactions between proteins

Researchers identify protective antibodies for rare, polio-like disease in children

Novel technology significantly improves the quality of stem cells

Researchers discover protein involved in protecting B cells

Mouse models help understand the functioning of muscles

Fantastic Muscle Proteins And Where To Find Them

Inhibitory interneurons excite the developing brain, study finds

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Intron detention is integral to post-transcriptional regulation mechanism

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

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