therapeutics News and Research

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Study shows how neurons communicate when confronted with stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, and Ludmila Belayev, MD, LSU Health New Orleans Professor of Neuroscience, Neurology and Neurosurgery, has unlocked a key fundamental mechanism in the communication between brain cells when confronted with stroke.

7 Aug 2020

Synthetic peptide makes multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

7 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

Identifying a new genetic cause of inherited neuropathy

Inherited mutations in a gene that keeps nerve cells intact were shown, for the first time, to be a driver of neuropathy known as Charcot-Marie-Tooth disease.

4 Aug 2020

New study can help develop longevity-promoting drugs

Scientists have successfully dialed up and down the lifespan of creatures by changing the activity of proteins present in roundworm cells.

4 Aug 2020

Re-engineering antibodies to fight SARS-CoV-2 infection

With millions of COVID-19 cases reported across the globe, people are turning to antibody tests to find out whether they have been exposed to the coronavirus that causes the disease.

31 Jul 2020

Novel therapeutics targeting primary cilia may reverse neurodevelopmental disorders

Primary cilia are structures that act like antennas for cells to identify signals and occur less in mice affected by Fragile X syndrome since birth.

31 Jul 2020

Experimental mRNA-based vaccine protects animals against SARS-CoV-2

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

27 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Simple DNA repeats can be the basis for genetic computers

Dr. Herbert asks what if our genome was far smarter than everyone previously believed? What if in the many DNA repeat elements lay the foundation for building a novel type of biocomputer?

22 Jul 2020

Scientist receives DoD grant to develop freeze-dried synthetic platelets

A Case Western Reserve University scientist, who has for more than a decade pioneered research into synthetic platelet substitutes, has been awarded a $3.8 million grant by the U.S. Department of Defense (DOD) to develop freeze-dried artificial platelets that can treat bleeding in wounded soldiers in the battlefield before they can be taken to a hospital.

22 Jul 2020

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy.

22 Jul 2020

Novel nano drug candidate kills triple negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

21 Jul 2020

Study sheds light on protein involved in Huntington’s disease

Researchers have performed a new study that exposes complex details regarding the biology of the huntingtin protein (HTT), which causes Huntington’s disease.

20 Jul 2020

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

On July 1, the Texas A&M Engineering Experiment Station's (TEES) National Center for Therapeutics Manufacturing (NCTM) received funding from the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) to help find a way to prevent the SARS-CoV-2 virus from binding to cells, protecting people from future infections.

20 Jul 2020