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New cellular pathway can protect cells from infection by Ebola virus, coronavirus

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020

First lethal mouse model established for COVID-19 infection

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

28 Aug 2020

Genetic background influences cancer risk in individuals with single-gene variants

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

21 Aug 2020

Female reproductive tract capable of mediating post-mating sexual selection

The female reproductive tract has the final say in human mate choice, according to new research from the University of Eastern Finland.

20 Aug 2020

Researchers develop new, rapid test to diagnose COVID-19

A revolutionary test developed by scientists can now diagnose COVID-19 within 20 minutes.

18 Aug 2020

Novel receptor protein can be a promising treatment for COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

18 Aug 2020

COVID-19 pandemic lessons could help mitigate climate change

The dynamics of the ongoing COVID-19 pandemic around the world could provide a valuable understanding of the efforts to reduce climate change.

17 Aug 2020

Organ-on-a-chip research explores link between ovarian cancer and blood cells

Recent discoveries made by researchers at Texas A&M University could change the way ovarian cancer is understood and treated.

17 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Exercise induces changes in sweat biomolecule levels, shows study

A new study shows that in addition to blood, endurance exercise induces changes in sweat biomolecule levels. These findings lay the groundwork for the development of future noninvasive exercise monitoring systems that utilize sweat as a biomarker source.

13 Aug 2020

Enzyme in the gut could provide a useful biomarker for intestinal diseases

Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications.

12 Aug 2020

Adapting the equipment and expertise of agtech labs could help combat pandemics

Just as redeploying a fleet of small British fishing boats helped during the Battle of Dunkirk, marshalling the research equipment and expertise of the many agtech labs around the world could help combat pandemics, say the authors of a just-published article in Nature Biotechnology.

11 Aug 2020

New UK supply contract for COVID-19 sample collection kits

EKF Diagnostics Holdings plc, the AIM listed point-of-care business, announces that it has received an initial order worth £3 m from a partner from the private sector to supply PrimeStore MTM, a novel patented sample collection device, to be used in a COVID-19 testing programme for UK staff.

From EKF Diagnostics 5 Aug 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Peter S. Conti awarded 2020 Benedict Cassen Prize for pioneering work in cancer imaging

Peter S. Conti, MD, PhD, known for his pioneering work in the diagnosis and management of cancer, was awarded the Benedict Cassen Prize during the 2020 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Genomics study in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

13 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

Diagnostics News and Research

New cellular pathway can protect cells from infection by Ebola virus, coronavirus

First lethal mouse model established for COVID-19 infection

Genetic background influences cancer risk in individuals with single-gene variants

Female reproductive tract capable of mediating post-mating sexual selection

Researchers develop new, rapid test to diagnose COVID-19

Novel receptor protein can be a promising treatment for COVID-19

COVID-19 pandemic lessons could help mitigate climate change

Organ-on-a-chip research explores link between ovarian cancer and blood cells

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

Exercise induces changes in sweat biomolecule levels, shows study

Enzyme in the gut could provide a useful biomarker for intestinal diseases

Adapting the equipment and expertise of agtech labs could help combat pandemics

New UK supply contract for COVID-19 sample collection kits

A new cell-based gene therapy approach to correct hemophilia A

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Peter S. Conti awarded 2020 Benedict Cassen Prize for pioneering work in cancer imaging

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Genomics study in Black Americans could lead to precision prostate cancer therapies

New type of molecular editor can make precise changes in mitochondrial DNA

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