Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

High blood caffeine levels lower body fat and the long-term risks of type 2 diabetes, study finds

A high blood caffeine level might curb the amount of body fat a person carries and their risk of type 2 diabetes, suggests research published in the open access journal BMJ Medicine.

16 Mar 2023

Researchers provide an entirely new perspective on tissue oxygenation

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others.

2 Mar 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Role of clonal hematopoiesis as a broad driver of atherosclerosis

A group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), collaborating with institutions in the USA, has shown that acquired mutations in the gene encoding the protein p53 contribute to the onset of atherosclerotic cardiovascular disease.

18 Jan 2023

Molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Chronic heart failure induces dysfunction in the cell’s powerhouses, which is caused in part by an excess of an essential intermediate compound in energy production. Compensating for this by supplementing the diet could be a potential technique for treating heart failure.

26 Oct 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Cellular therapy leads to meaningful functional improvements in DMD patients

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

From The University of California, Davis 14 Mar 2022

Why is it Important to have Diverse Genomics Data in Science?

In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.

From MultiplAI Health 17 Feb 2022

Daily consumption of more olive oil linked to lower mortality risk

Consuming more than 7 grams (>1/2 tablespoon) of olive oil per day is associated with lower risk of cardiovascular disease mortality, cancer mortality, neurodegenerative disease mortality and respiratory disease mortality, according to a study publishing today in the Journal of the American College of Cardiology.

17 Jan 2022

CAR T cells produced in vivo using modified mRNA treat cardiac injury

A new study by researchers from the University of Pennsylvania shows that experimental immunotherapy can temporarily reprogram the immune cells of patients.

10 Jan 2022

In vivo generation of engineered CAR T cells to treat heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

7 Jan 2022