Stem Cells News and Research

RSS

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

New RNA Sequencing Technology Uncovers Molecular Drivers of Cellular Differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

8 Aug 2025

New Imaging System Reveals Cellular Activity at Unprecedented Depths

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

8 Aug 2025

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Ribosome Levels Drop During Early Brain Development

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

6 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

UCLA Researchers Reprogram Stem Cells to Produce Continuous Cancer-Fighting T Cells

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.

5 Aug 2025

Uncovering the Molecular Roots of Neural Stem Cell Decline

Age often brings a gradual decline in the ability to learn new things and retain memories. This phenomenon, often associated with the elderly, is linked to the brain's deteriorating capacity to generate new neurons-a process that primarily occurs in the hippocampus -as neural stem cells (NSCs) divide and mature.

28 Jul 2025

Neuron-Like Telocytes Directly Connect to Stem Cells in the Intestine

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

Researchers Combine AI and CRISPR to Rejuvenate Ovarian Function

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

21 Jul 2025

Study Reveals Hidden Function of So-Called Junk DNA

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression.

21 Jul 2025

New Metabolic Map Reveals How Blood Stem Cells Age and Become Diseased

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

16 Jul 2025

Understanding DNA's Complex 3D Architecture in the Cell

Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying cancer and muscular dystrophy.

14 Jul 2025

Evidence for Neural Stem Cell-Based Therapies in Multiple Sclerosis

Research indicates that neural stem cell transplants could promote myelin repair in progressive multiple sclerosis, paving the way for innovative treatments.

8 Jul 2025

Aligned Stem Cell Sheets Show Boosted Healing Potential

A new way to grow stem cells may help them release more of the signaling proteins they use to repair tissue, potentially improving future treatments.

4 Jul 2025

Scientists Grow Liver Organoids with Functional Blood Vessels

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology--producing liver tissue that grows its own internal blood vessels.

26 Jun 2025

Fluorescent Molecules Offer Unprecedented Insight into Cell Structures

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities.

25 Jun 2025

Genetic Tool Successfully Repairs Mitochondrial Mutations in Human Cells

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor.

25 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Histone Variant H2AZ1 Identified as Key Driver of Stem Cell Aging

Cellular senescence-a state of irreversible growth arrest accompanied by chronic inflammation-is a major contributor to aging and tissue degeneration.

18 Jun 2025

Placenta and Hormone Levels in the Womb May Have Been Key Driver in Human Evolution, Say Researchers

The placenta and the hormones it produces may have played a crucial role in the evolution of the human brain, while also leading to the behavioral traits that have made human societies able to thrive and expand, according to a new hypothesis proposed by researchers from the Universities of Cambridge and Oxford.

18 Jun 2025