Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

New patented technique reveals the energy status of cells

Scientists have developed a novel process that may help personalize anticancer treatments.

2 Dec 2020

Study: Gut microbiota directly shapes the makeup of human immune system

In recent years, the microbiota -- the community of bacteria and other microorganisms that live on and in the human body -- has captured the attention of scientists and the public, in part because it's become easier to study. It has been linked to many aspects of human health.

1 Dec 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

First functional analysis of cytokine IL-15L using rainbow trout

The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing binding capacity for receptor chain IL-15Rα. IL-15L was conserved in fishes, reptiles, and some mammals but lost in humans and mice.

23 Nov 2020

Discovering a new step in immune cell generation

In this interview, Dr. Shalin Naik speaks to AZoLifeSciences about his team's latest research that led to the discovery of a new step in the development of T and B cells that could help us to better understand leukemia.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 12 Nov 2020

White blood cells can be trained to attack tumor cells

Scientists at the National Center for Tumor Diseases Dresden (NCT/UCC) and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

9 Nov 2020

MUSC researchers demonstrate polarized Th17 cells can effectively eradicate tumors

Adoptive transfer of T-cells can extend survival and, at times, treat patients with advanced solid tumors.

2 Nov 2020

Checkpoint inhibitors offer a promising solution for hard-to-treat cancers

Cancer immunotherapies, which empower patients' immune systems to eliminate tumors, are revolutionizing cancer treatment. Many patients respond well to these treatments, sometimes experiencing long-lasting remissions. But some cancers remain difficult to treat with immunotherapy, and expanding the impact of the approach is a high priority.

2 Nov 2020

New type of cancer immunotherapy trains the immune system to eliminate tumor cells

A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.

2 Nov 2020

“Nanobiologic” immunotherapy can train the immune system to eliminate tumor cells

Until recently, it was believed that the innate immune system, the body's first line of defense, lacked the ability to remember pathogens like the adaptive immune system.

2 Nov 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Scientists use new model to develop specific cancer immunotherapy

The function of the body’s immune system is to defeat diseases by detecting foreign invaders and then mounting a response against these pathogens.

28 Oct 2020

Researchers identify new potential therapeutic targets for SARS-CoV-2 infection

To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.

27 Oct 2020

Immunotherapy News and Research

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

New patented technique reveals the energy status of cells

Study: Gut microbiota directly shapes the makeup of human immune system

Study explains why immunotherapy works on certain patients with head and neck cancer

First functional analysis of cytokine IL-15L using rainbow trout

Discovering a new step in immune cell generation

White blood cells can be trained to attack tumor cells

MUSC researchers demonstrate polarized Th17 cells can effectively eradicate tumors

Checkpoint inhibitors offer a promising solution for hard-to-treat cancers

New type of cancer immunotherapy trains the immune system to eliminate tumor cells

“Nanobiologic” immunotherapy can train the immune system to eliminate tumor cells

'Training’ the innate immunity may improve the success of immunotherapy

Scientists use new model to develop specific cancer immunotherapy

Researchers identify new potential therapeutic targets for SARS-CoV-2 infection

Novel technique could propel personalized treatments for cancer

Genomic differences can help develop more personalized treatments for African American men

Study shows antibody-based drug could reduce cancer in mice

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Novel approach based on microfluidic technology to fight cancer

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