Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Changes in epigenome responsible for reduced stem cell function upon aging

The bones become thinner with age, resulting in frequent fractures and making them susceptible to bone diseases like osteoporosis.

From The Max Planck Institute 20 Sep 2021

NANOG protein ameliorates primary hallmarks of cellular senescence, says study

Researchers have found that a protein named after the mythical land of youth in Irish folklore is efficient at reversing skeletal muscle cells aging.

20 Sep 2021

New Cornell study finds potential treatment for MRSA ‘superbug’

A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.

17 Sep 2021

Scientists use stem cells to investigate the genetic risk for Alzheimer's disease

AD, the most frequent cause of dementia, affects an estimated 24 million people worldwide. With very limited treatment options, scientists are looking for ways to understand the disease better.

16 Sep 2021

Researchers reconstruct structures in the ovarian environment using mouse stem cells

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells.

15 Sep 2021

Stem cell transplantation leaves no scars in the DNA of transplanted cells

Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure.

8 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

Brain cholesterol promotes toxic amyloid plaque formation in Alzheimer’s disease

Research has revealed higher cholesterol supply from astrocytes to neurons in the model of Alzheimer’s disease (AD) brains.

31 Aug 2021

Researchers create cardiomyocyte model using a genetic algorithm

Human-induced pluripotent stem cells can differentiate into cardiac myocytes and are employed in applications like formulating patient-specific disease models.

31 Aug 2021

Study uncovers mechanism behind skin cell transformation

Researchers have created a recipe for turning skin cells into primitive muscle-like cells that can be sustained indefinitely in the laboratory.

23 Aug 2021

Newly developed premature cells can support early heart development

A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.

23 Aug 2021

Study identifies gene families responsible for simple leaf development

Recent research elucidates how simple leaves—one of the two basic forms of leaves—originate in a plant.

18 Aug 2021

Researchers develop method to preserve high-quality cultured stem cells for a long time

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

16 Aug 2021

Researchers use prime editing to correct mutations causing cystic fibrosis in organoids

A team of scientists rectified mutations that result in cystic fibrosis in cultured human stem cells.

11 Aug 2021

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Cambridge scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a study published in Communications Biology, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells.

6 Aug 2021

Researchers create non-invasive imaging technology to predict stem cell differentiation

Stem cell research exhibits significant potential for regenerative therapies and treatments to fight against cardiovascular disease.

29 Jul 2021

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord.

28 Jul 2021

New test to detect substances that are harmful to the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021