Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

AstroID Database Organizes Billions of Cancer Cells Into Searchable Hierarchical Tiers

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data - including laboratory results, genetic sequencing and imaging data - in one setting.

5 Mar 2026

Blood Tau217 Test Predicts When Alzheimer’s Symptoms May Begin

The %p-tau217 biomarker in blood offers a novel approach to estimate Alzheimer's onset, potentially transforming prevention trial strategies.

5 Mar 2026

Study Warns AI Often Predicts Gene Mutations by Looking at Unrelated Traits

New research warns that popular deep learning systems trained for cancer pathology may be relying on hidden shortcuts rather than genuine biological signals.

3 Mar 2026

Human 3D Model Shows How the Gut Drives Neurodegeneration

Research on a 3D microfluidic model highlights gut-brain interactions, offering new insights into inflammatory processes linked to neurodegenerative diseases.

18 Feb 2026

Tumor Environment Constrains Cellular Signal Carrying Vesicles

A new study may change the way scientists think about the distance traveled by tiny bubbles carrying signals between cells that are embedded in tissue.

12 Feb 2026

Aged Neutrophils With CCL3 Drive Tumor Growth Across Cancers

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

Human Neurons Reveal Why Some Cells Resist Tau Protein Buildup

New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient than others to the buildup of a toxic protein that is a hallmark of Alzheimer's disease and related dementias, potentially leading to new targets for therapies or treatments.

31 Jan 2026

New Technology Links Extracellular Vesicles Directly to Producing Cells

Extracellular vesicles and particles are central to how cells communicate, especially in cancer, where they help shape metastasis and treatment resistance.

30 Jan 2026

Maternal And Fetal Cell Exchange Shapes Health Across Multiple Generations

During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

24 Jan 2026

Engineered Human Skin Acts as a Living Biosensor for Inflammation

Implanted living skin-based biosensors offer a breakthrough in inflammation tracking, providing real-time biomarker monitoring without invasive procedures.

21 Jan 2026

Study Reveals Circadian Control of Immune Variability

In laboratory models, researchers at The University of Texas MD Anderson Cancer Center discovered that a mother's circadian rhythms, or internal body clock, can influence the immune system states of her offspring, which can accurately predict the risk of bacterial infection.

5 Jan 2026

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

24 Dec 2025

Light-Based Technique Reveals How Extracellular Vesicles Interact With Cells

The tiny bubbles that carry signals between cells throughout the body were discovered decades ago, but precisely what they contain and how their cargo affects recipient cells is still largely a mystery.

12 Dec 2025

Broken DNA Loops Trigger Lymphoma Development

Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear, isolating communities from vital resources.

8 Dec 2025

Unraveling How GFAP Mutations Disrupt Mitochondria in Alexander Disease

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare.

2 Dec 2025

New "Ultra-Mild" Method Corrects Cancer DNA Methylation Test Errors

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature Communications. UMBS-seq achieves both accuracy and gentleness, unlocking more reliable cancer biomarker detection.

13 Nov 2025

Oxidative Stress May Hold Clues to the Origins of Repetitive Behaviors

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S.

6 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025

Study Reveals Shared Genetic Roots Between ALS and Hereditary Spastic Paraplegia

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct.

3 Nov 2025