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Semaphorin 3E Emerges as a Key Factor in Female Reproduction

The discovery of the Sema3E pathway in ovulation by Cornell researchers could enhance understanding of infertility and improve reproductive health strategies.

13 Jun 2025

Proteomic Signature in Blood Predicts Dementia and Diabetes Risk

A blood-based proteomic signature predicts healthspan, linking protein levels to disease risk and mortality, paving the way for targeted aging interventions.

10 Jun 2025

Targeting the Chagas Parasite by Interrupting Its Lifecycle

Chagas disease is often called a silent killer because many people don't realize they have it until complications from the infection kill them.

9 Jun 2025

IL-12 Adjuvant Shows Promise in Boosting T-Cell Immunity

Scientists are always searching for new weapons to add to their arsenal in the pursuit of creating vaccinations that would better support the body’s immune system in fending off disease.

9 Jun 2025

Unraveling the Genetic Roots of Anemia in Inflammatory Bowel Disease

One of the most frequent side effects of inflammatory bowel disease, or IBD, is iron deficiency and anemia, which can be made worse by a genetic mutation linked to Crohn’s disease, according to a study conducted by biomedical scientists at the University of California, Riverside School of Medicine.

9 Jun 2025

Breakthrough Gene Discovery Uncovers a Master Switch for Food Intake

The Gpr45 gene is linked to food intake regulation, offering insights for obesity therapies. Study utilizes Automated Meiotic Mapping for gene identification.

6 Jun 2025

Newly Identified Molecules from Blood Bacterium Show Promise in Combating Skin Aging

Indole metabolites from the blood bacterium P. sanguinis demonstrate potential in anti-aging skin treatments by lowering inflammation and oxidative damage.

6 Jun 2025

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

Novel Peptide Shows Promise in Fighting Deadly, Drug-Resistant Bacteria

A study identifies a new antimicrobial peptide that effectively targets gram-negative bacteria, highlighting its potential in combating antibiotic resistance.

5 Jun 2025

Gene Editing Using CRISPR and AAV6 Impacts Long-Term Regeneration of Blood Stem Cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

4 Jun 2025

Study Reveals Key Proteins Behind CAR-T Cell Therapy Effectiveness

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Canine DNA Reveals New Genes Linked to Gastric Cancer In Humans

Dogs share our homes, our habits and sometimes, our diseases. Gastric cancer is rare in dogs, but when it does strike, it closely resembles gastric cancer in humans: subtle clinical signs, comparable tumor subtypes, late-stage diagnosis and poor outcomes.

3 Jun 2025

New Diagnostic Tool Enhances Early Detection of Viruses with Powerful Bioluminescence

Mass General Brigham researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing complex biological samples.

2 Jun 2025

Common Genetic Variation Doubles Dementia Risk in Men, Study Finds

Research reveals men with a genetic variant may face double the dementia risk compared to women, highlighting the need for targeted prevention strategies.

2 Jun 2025

UVA Research Reveals Key to HIV Latency

University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.

30 May 2025

How Microbiome Changes Contribute to Cardiovascular Aging

UZH researchers uncover how gut bacteria affect cardiovascular health, revealing phenylacetic acid's role in blood vessel aging and heart disease development.

29 May 2025

Protein Mapping Uncovers 'Molecular Fingerprint' for Insulin Sensitivity

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

28 May 2025

Extracellular RNA Profiling Recommendations: Results From exRNAQC, a Comprehensive Assessment of Pre-Analytical Factors for Quality Control

A large-scale study (exRNAQC) outlines how blood tube type, RNA purification method, and processing time influence exRNA profiles. Results support new guidelines for researchers and diagnostic product developers working on RNA-based biomarkers.

28 May 2025

Peptide Metabolites: A New Frontier in Antiviral Therapies

Interest in antiviral treatments has grown significantly since the COVID-19 pandemic. Effective peptide treatments made from natural substances are in high demand right now due to the increased attention being paid to peptide-based drugs like Wegovy.

27 May 2025

New Stem Cell Islet Model Mimics Pancreatic Function More Accurately

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

24 May 2025