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KARAP Deficiency Enhances Macrophage IL-10 Production and Epithelial Barrier Repair

Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease in which persistent mucosal inflammation damages the epithelial barrier.

5 Nov 2026

Biomimetic Protein Scaffolds Enable Living Dentin Regeneration in Dental Cavities

A protein that helps build teeth may one day be used to allow damaged teeth to repair themselves.

5 Nov 2026

Novel Molecular Bridge Links Coagulation Cascade with Cancer Hormonal Environment

New Cleveland Clinic research published in Cancer Cell shows that people with glioblastoma have more active platelets, which are cells involved in blood clotting. Platelets also communicate with other cells and can influence immune activity.

4 Nov 2026

Innate Immune Sensor cGAS Acts as Nuclear Metabolic Regulator

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

4 Nov 2026

CRISPR Screen Uncovers COMPASS Pathway Role in Suppressing Gut Autoimmunity

Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance.

3 Nov 2026

UCLA Health Study Identifies Strategy to Boost Strength and Longevity of Cancer Fighting T Cells

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a promising new strategy to make cancer-fighting immune cells stronger and potentially longer-lasting, a discovery that could help improve the effectiveness of immunotherapies that use a patient's own immune cells to attack cancer.

31 Oct 2026

Targeting the Blood-Brain Barrier Using Sodium-Dependent Multivitamin Transporter Protein Systems

Researchers at the University of Eastern Finland have identified a transporter protein with the potential to open new avenues for improving creatine delivery into the brain and for developing other therapies targeting the central nervous system.

31 Oct 2026

Dinosaur Blood – Oldest Discovery Rewrites What Fossils Can Reveal About the Past

An international research team led by Curtin University has for the first time uncovered unequivocal evidence of fossilized red blood cells and amino acids of collagen, fundamentally reshaping our understanding of fossil preservation and molecular longevity in deep time.

30 Oct 2026

Cytosolic Glucose and Mitochondrial Lactate Oxidation Prevent Energetic Collapse

The heart is the hardest-working muscle in the body, beating constantly no matter what the body’s energy reserves look like.

30 Oct 2026

Aberrant RNA Splicing Generates Immunogenic Neoantigens in Systemic Lupus

Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual mutations that may turn their bodies into battlegrounds.

30 Oct 2026

Blood Pressure Pregnancy Clue Could Open Door to New Treatments

Researchers at the University of Manchester and Manchester University NHS Foundation Trust have uncovered a hidden defect in the tiny blood vessels of women with preeclampsia, a dangerous and common pregnancy complication which can threaten the lives of both mother and baby.

28 Oct 2026

Fast-Acting Marine Compound Targets Fatal Brain-Eating Amoeba Infection

Primary amoebic meningoencephalitis (PAM), a parasitic disease that causes the rapid deterioration of brain tissue, is one of the most lethal infections known, with a fatality rate exceeding 97%.

28 Oct 2026

Why a Breakthrough Blood Cancer Drug Could be Better for Patients

A more effective and better-tolerated treatment for chronic myeloid leukaemia (CML) could improve quality of life for people living with the disease.

27 Oct 2026

Taurine Deficiency Triggers Innate Immune Sensing of Cellular Danger Signals

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

26 Oct 2026

Long-Read Nanopore Sequencing Resolves Unexplained Tumor Mutations

Michigan's Oncology Sequencing Program, or MiOncoSeq, was the first of its kind in the nation to sequence patient tumors.

24 Oct 2026

New Genetic Map Identifies Variations Linked to Long QT Syndrome

Using an innovative, high-throughput technique, an international collaboration led by Vanderbilt Health researchers has created a "map" of 1,757 genetic variations that can trigger a life-threatening heart rhythm disorder called long QT syndrome.

24 Oct 2026

Metabolic Reprogramming Enhances Gamma Delta CAR T Solid Tumor Clearance

By turning a patient's own immune cells into stronger cancer-fighting cells, CAR T-cell therapy has transformed how some blood cancers are treated. But it's been harder to extend this approach to solid tumors, including cancer that has spread to the bone.

21 Oct 2026