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How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026

Scientists Uncover the Molecular Fingerprints of mRNA Vaccine-Induced T Cells

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel-prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, small cell lung cancer and bladder cancer, among others, opening the door to new ways of preventing and treating the disease.

17 Apr 2026

"Zombie" Macrophages Accumulate in Aging Tissues and Diseased Livers

UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice - even while the animals remained on an unhealthy diet.

16 Apr 2026

Largest Genetic Study Reveals New Biological Clues for Severe Pregnancy Sickness

The USC research team that recently identified the hormone-encoding gene GDF15 as a key driver of pregnancy sickness has identified 9 additional genes linked to its most severe form, hyperemesis gravidarum (HG).

15 Apr 2026

Identifying Somatic Driver Mutations in Thyroid Autoimmune Disease

According to recent studies, immune cell DNA mutations that eliminate the immune system's natural brakes may be the cause of autoimmune disorders.

15 Apr 2026

Early Epigenetic Changes and Gut Microbiome Interact to Shape Neurodevelopment

The gut microbiome and epigenetics-molecular switches that turn genes on or off-are intertwined, and both contribute to neurodevelopment, finds a study publishing April 10 in the Cell Press journal Cell Press Blue.

13 Apr 2026

CU Boulder Study Shows Genetic Link Between Mental and Physical Illness

For centuries, mental illness and physical disease have been viewed as two distinct categories, each with its own field of study, its own doctors, and its own menu of treatments.

10 Apr 2026

New Experimental System Mimics Low-Grade Pediatric Glioma in 3D

A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.

10 Apr 2026

Janelia Scientists Develop New Method To Study Blood-Brain Barrier Proteins

Think it was hard to get into Studio 54? Try getting through the blood-brain barrier.

10 Apr 2026

Non-Coding DNA Mutations Identified as Cause of Rare Neonatal Diabetes

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies.

10 Apr 2026

Single-Cell Mapping Uncovers Insights Into Pregnancy Complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

9 Apr 2026

Mosaic Cell Reprogramming Primes Skin for Rapid Injury Response

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

9 Apr 2026

RNU2-2 Variants Drive Most Common Recessive Neurodevelopmental Disorder

New findings on RNU2-2 syndrome highlight its role in neurodevelopmental disorders, emphasizing genetic counseling and early diagnosis for affected families.

9 Apr 2026

ASHOP Platform Unifies Multi-Omics Data for Blood Cancer Insights

Scientists at St. Jude Children's Research Hospital, the American Society for Hematology (ASH) and the Munich Leukemia Laboratory have developed a data-sharing platform that unites genomics, gene expression and clinical information from nearly 6,000 patients with blood cancers.

7 Apr 2026