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Clinician-Led Approach Could Give Doctors a Control Dial for Cell Therapies

A clinician-led research team has developed a gene-editing platform that could give doctors more control over cell therapies, making them more practical for patients with complex immune conditions.

20 Oct 2026

Study Details Genetic Divergence Between Astrocytomas and Oligodendrogliomas

Treatment-resistant brain cancers develop different mutations as they become more aggressive, according to new research from Yale School of Medicine.

20 Oct 2026

Collective Cell Migration Establishes Tissue Scale Planar Cell Polarity

From the hairs on our arms to the microscopic sensory structures of the inner ear, many tissues in the body are built with a clear sense of direction.

20 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Live Organelle Imaging Catches Early Neuronal Stress Before Cell Death

Scientists studying amyotrophic lateral sclerosis (ALS), Parkinson's, Alzheimer's and other neurological diseases are getting unprecedented views inside brain cells, using powerful new microscopes to uncover changes that may begin long before neurons die.

20 Oct 2026

Study Details Mechanisms Driving Irreversible Fungal Cell Wall Fusion

The fusion of two cells is a decisive event in the sexual reproduction of many organisms. In fungi, cells must not only bring their membranes together and merge them, but also locally open their protective cell wall.

20 Oct 2026

Mayo Clinic Study Advances Detection of Somatic DNA Mutations

Researchers in a Mayo Clinic-led study have shown how to detect a broad range of DNA mutations in noncancerous human tissues and across the genome.

16 Oct 2026

Cedars-Sinai Expands Stem Cell Research Aboard the Space Station

When NASA’s SpaceX CRS-35 mission docks with the International Space Station Oct. 15, it will deliver two experiments from the Cedars-Sinai Center for Space Medicine Research.

16 Oct 2026

Korean Researchers Identify New Mechanism Underlying Superbug Antibiotic Resistance

A joint research team led by Professor Hongbaek Cho of the Department of Biological Sciences at Sungkyunkwan University (SKKU) and Professor Jeong Min Chung of the Department of Biotechnology at The Catholic University of Korea has identified a new mechanism underlying antibiotic resistance in Pseudomonas aeruginosa, a major multidrug-resistant "superbug."

16 Oct 2026

Intestinal Cells Use Signal Rhythms to Determine Cell Growth

A study conducted at the Hubrecht Institute reveals that the intestines use the rhythm of a signal to decide which cells to make.

16 Oct 2026

Machine Learning Tool Pinpoints Crucial Gene Regulation Changes

Changes in our genes affect health risks from heart disease to cancer, but how those genes are turned on and off is just as crucial to health.

16 Oct 2026

Balancing Immune Cells May Unlock Hidden Human Regenerative Potential

In a study of fingertip regeneration, a team led by JAX Senior Research Scientist James Godwin found that some immune cells in mice can attack and kill cells needed to rebuild bone, while a subset of those same immune cells can protect the bone-making cells and allow regeneration to continue.

16 Oct 2026

Novel Molecular Pathway Identified to Combat T-Cell Exhaustion in Cancer

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ability to keep tumors under control.

16 Oct 2026

Could mRNA Vaccine Technology Help Repair Damaged Livers?

Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery.

16 Oct 2026

Cell Division Actively Reshapes Crowded Epithelial Tissue, Study

Every time a tissue grows or renews itself, cells must divide inside an already crowded environment.

16 Oct 2026

Targeted Interneuron Manipulation Improves Learning and Memory Processing Capabilities

Researchers were able to restore the function of neurons linked to cognitive function and information processing in mice that mimic key features of Alzheimer's disease, showing early promise for the development of a similar targeted therapy in humans.

16 Oct 2026