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Computational Tool Maps the Dance of Circadian Synchrony

Computational Tool Maps the Dance of Circadian Synchrony

What makes someone a "morning lark" or a "night owl?" Why does jet lag hit us so hard, and why do some people struggle each winter with seasonal affective disorder?

26 Dec 2025

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Engineered EVs Offer a Modular and Clinically Adaptable Immune-Tolerance Platform

Engineered EVs Offer a Modular and Clinically Adaptable Immune-Tolerance Platform

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

24 Dec 2025

New 3D Model Reveals Crucial Interactions During Early Embryo Development

New 3D Model Reveals Crucial Interactions During Early Embryo Development

By engineering a system replicating the womb lining with high biological accuracy, researchers at the Babraham Institute and Stanford University have been able to study the implantation of human embryos, opening up this enigmatic process to investigation.

24 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

Stem Cell Models Offer Insights Into Early Brain Development and Autism

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

24 Dec 2025

Kinetic Traps Explain Differences in GPCR Drug Efficacy

Kinetic Traps Explain Differences in GPCR Drug Efficacy

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to transmit signals inside the cell.

23 Dec 2025

Mapping the Four Dimensional Organization of the Human Genome

Mapping the Four Dimensional Organization of the Human Genome

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

Study Challenges Long-Held Assumptions About Mendelian Retinal Disorders

Study Challenges Long-Held Assumptions About Mendelian Retinal Disorders

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

New vCATCH Method Maps Drug Binding Across Every Cell in the Body

New vCATCH Method Maps Drug Binding Across Every Cell in the Body

When you take a drug, where in your body does it actually go? For most medications, scientists can make only educated guesses about the answer to this question.

23 Dec 2025

Passive Adaptation Balances Protein Synthesis and Degradation in Cells

Passive Adaptation Balances Protein Synthesis and Degradation in Cells

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

23 Dec 2025

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Calcium Signaling Suppresses Lignin Accumulation in Pear Stone Cells

Stone cells arise from lignified secondary cell walls and cause a gritty texture, reduced sweetness, and poor flavor in many pear cultivars.

23 Dec 2025

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

The researchers have succeeded in tracing two classic hallmarks of cancer – the evasion of apoptosis (a form of programmed cell death) and the dysregulation of energy metabolism – back to a common molecular mechanism.

23 Dec 2025

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch BioLabs (WBL), a leader in native, long-read sequencing and epigenomic analysis, today announced a co-marketing agreement with Agilent Technologies to support the adoption of its Direct Targeted Methylation Sequencing (dTMS) platform.

22 Dec 2025

Study Identifies Protein Target to Overcome Drug Resistance in NSCLC

Study Identifies Protein Target to Overcome Drug Resistance in NSCLC

Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States.

22 Dec 2025

Condensates Introduce a New Paradigm in Cellular Bioelectricity

Condensates Introduce a New Paradigm in Cellular Bioelectricity

Many biological processes are regulated by electricity-from nerve impulses to heartbeats to the movement of molecules in and out of cells.

19 Dec 2025

Study Reveals Glucose-Driven Mitochondrial Migration in Beta Cells

Study Reveals Glucose-Driven Mitochondrial Migration in Beta Cells

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

19 Dec 2025

New Method Enables Direct Freezing of iPS Cells in Culture Dishes

New Method Enables Direct Freezing of iPS Cells in Culture Dishes

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without losing their viability or undifferentiated state after thawing.

19 Dec 2025

Elusive Kinase State Explains How Cells Achieve Efficient Signaling

Elusive Kinase State Explains How Cells Achieve Efficient Signaling

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its target, without needing to release

19 Dec 2025

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

Researchers Uncover Gene Control Elements Tied to Alzheimer’s Disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

19 Dec 2025

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