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Revive Penicillin’s Power by Exploiting Bacteria’s Hidden Weakness

When many disease-causing bacteria come into contact with penicillin, they do not necessarily die immediately, but instead enter a brief survival mode known as antibiotic tolerance.

13 Mar 2026

Dual Mechanism of Deep-Sea Sponge Compound Suppresses Cancer Cell Proliferation

A collaborative research team led by Professor Kaori Sakurai at Tokyo University of Agriculture and Technology, together with Associate Professor Hiroaki Itoh and Professor Masayuki Inoue at Graduate School of Pharmaceutical Sciences, the University of Tokyo, has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan.

12 Mar 2026

Novel INSTALL Technology Achieves Non-Toxic Gene Integration in Multiple Cell Types

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

12 Mar 2026

Study Reveals How Altering Cancer’s Protein Machinery Stimulates Antitumor Immunity

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response.

12 Mar 2026

Functional Mitochondria Key to Recovery of Dying Photoreceptor Cells

Photoreceptors are specialized cells in the eye that convert light energy into neural signals.

12 Mar 2026

Gut Microbes Reshape Ovarian Aging in Mice

Findings indicate gut microbes impact ovarian function in mice, offering insights into reproductive aging and potential microbiome-based health interventions.

12 Mar 2026

Newly Discovered Neurons Respond to Complex Spatial Frequencies

The visual cortex is the part of the brain that enables visual perception. In this area millions of nerve cells, called neurons, process stimuli from the outside world.

11 Mar 2026

Study Reveals Microbiome Role in Protecting the Colon From Tissue Injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

11 Mar 2026

Computational Tool Improves Detection of Microbes in Tumor Sequencing Data

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how they grow, evade immunity or respond to treatment.

11 Mar 2026

Cardiff University Decodes Catastrophic DNA Rearrangement

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

11 Mar 2026

How SARS-CoV-2 Hijacks Host tRNA Chemistry to Sustain Infection

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

11 Mar 2026

mAbxience Selects Genedata Bioprocess to Automate End-to-End CDMO Workflows

Genedata, a Danaher company and the leading provider of enterprise software solutions for biopharmaceutical R&D, today announced that mAbxience has selected the Genedata Bioprocess® enterprise platform to structure and harmonize all bioprocess development data across its operations.

From Genedata AG 11 Mar 2026

Whole-Cell Simulation Recreates Molecular Dynamics of Minimal Living Cell

By simulating the life cycle of a minimal bacterial cell - from DNA replication to protein translation to metabolism and cell division - scientists have opened a new frontier of computer vision into the essential processes of life.

10 Mar 2026

Advanced Genome Sequencing Reveals Hidden Genetic Variants Linked to Autism

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads large sections of the genome at once, making it easier for scientists to find new genetic variants and understand how genetic variants affect the function of a gene.

10 Mar 2026

Setd8 Enzyme Preserves Retinal Progenitor Identity During Eye Development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

10 Mar 2026

Mechanical Forces Inside Tumors Promote Breast Cancer Growth and Invasion

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

10 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

Discovery of Nuclear Metabolic Fingerprints Offers New Insights Into Cancer

More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published today in Nature Communications.

9 Mar 2026

ANKIB1 Identified as the Essential Master Switch for Innate Immunity

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.

9 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026