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Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

22 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss. Teeth have an intrinsic capability to regenerate, a process which is driven by dental pulp stem cells (DPSCs) which replenish the dental pulp including the dentin-producing cells called odontoblasts.

22 May 2026

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.

21 May 2026

New Epigenetic Study Discovers Inheritance Patterns That Defy Mendel's Laws

Scientists have long known that the DNA code in genes is not the only way to pass genetic traits from parents to offspring.

21 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Genetic Engineering Creates an Immune System Cloak to Extend Bacterial Drug Circulation

While previous research from Johns Hopkins University is successfully completing clinical trials, University of Rhode Island College of Pharmacy Assistant Professor Kaitlin Dailey is expanding on that work to more specifically target tumors that are difficult or impossible to access, especially those associated with pancreatic cancer-one of the deadliest types.

21 May 2026

New Study Finds Primates Are at Greater Risk of Picking Up Human Diseases Thanks to Deforestation

For the first time researchers have found evidence that monkeys are catching human Hepatitis B virus (HBV) in the Amazon and deforestation could be making the problem much worse.

20 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

Novel Synthetic Molecules Attack Cell Membranes to Prevent Severe Bacterial Infections

In a new study, researchers show how so‑called TriPcides can target the bacterium Staphylococcus aureus, including antibiotic‑resistant strains such as MRSA. The compounds disrupt the bacteria's ability to cause infection and can also kill dormant bacterial cells, which are often difficult to treat with existing antibiotics.

20 May 2026

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

A peer-reviewed invited review published today in Genomic Psychiatry argues that the adult brain, when it learns and remembers and rewires, is not inventing something new.

20 May 2026

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma.

20 May 2026

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient cell functions.

20 May 2026

Copper-Free Click Reactions Allow Safe In Vivo Tracking of Tumors Inside the Body

Conventional cancer treatments like chemotherapy often struggle with poor targeting, leading to severe systemic toxicity and drug resistance. Diagnostic techniques, while improving, are frequently invasive and cannot monitor treatment responses in real time.

20 May 2026

Microbes Switch Functional States Without Genetic Mutations to Withstand Stress

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes.

20 May 2026

Can Everyday Supplements Lead to Failed Anti-Doping Tests?

Researchers developed a high-throughput LC-MS/MS platform that screened 331 pharmacologically active compounds and quantitatively validated 214 analytes across representative food matrices. Applied to 78 commercial foods and supplements, the framework showed that some products could produce modeled urinary concentrations exceeding WADA reporting thresholds under realistic intake scenarios.

19 May 2026

Low-Oxygen Environments Enhance Engraftment and Function of Transplanted Stem Cells

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that human hematopoietic stem cells are highly sensitive to oxygen, which can dictate how the cells grow and function.

19 May 2026

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore), has identified eight new "signatures" of DNA patterns (gains and/or losses) in breast cancer.

19 May 2026

Clinical News and Research

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

Dental Pulp Stem Cell Subsets Triggers Rapid Cellular Senescence and Tooth Decay

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

New Epigenetic Study Discovers Inheritance Patterns That Defy Mendel's Laws

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Genetic Engineering Creates an Immune System Cloak to Extend Bacterial Drug Circulation

New Study Finds Primates Are at Greater Risk of Picking Up Human Diseases Thanks to Deforestation

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Novel Synthetic Molecules Attack Cell Membranes to Prevent Severe Bacterial Infections

Researchers Compare Embryonic and Adult Mouse Brain Targets to Map Memory Networks

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Copper-Free Click Reactions Allow Safe In Vivo Tracking of Tumors Inside the Body

Microbes Switch Functional States Without Genetic Mutations to Withstand Stress

Can Everyday Supplements Lead to Failed Anti-Doping Tests?

Low-Oxygen Environments Enhance Engraftment and Function of Transplanted Stem Cells

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

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