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Computational Brain Model Predicts Errors, Uncovers Previously Unseen Neurons

A new computational model of the brain based closely on its biology and physiology not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the discovery of counterintuitive activity by a group of neurons that researchers working with animals to perform the same task had not noticed in their data before, said a team of scientists at Dartmouth College, MIT, and the State University of New York at Stony Brook.

30 Dec 2025

Genomic Test Can Accurately Identify Early Recurrence Risk in Prostate Cancer Patients

A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face the highest burden from this disease.

26 Dec 2025

Stem Cells Mimic Earliest Stages of Brain Development in a Dish

Researchers have made great strides to understand early signs of autism. Studies have found that certain factors like genetics, sleep deprivation, excess fluid in the brain-and brain size-can increase the risk of neurodevelopmental conditions, like autism.

26 Dec 2025

Antibiotic Resistance: A Global Crisis Threatening Modern Medicine's Future

Once a medical miracle, antibiotics are now losing their power. Across the world, common infections are becoming harder-and sometimes impossible-to treat. This new review paints a sobering picture of global antimicrobial resistance (AMR), tracing how bacteria and fungi are evolving faster than medicine can respond.

24 Dec 2025

New 3D Model Reveals Crucial Interactions During Early Embryo Development

By engineering a system replicating the womb lining with high biological accuracy, researchers at the Babraham Institute and Stanford University have been able to study the implantation of human embryos, opening up this enigmatic process to investigation.

24 Dec 2025

Researchers Find Enzyme That Controls Fat Production, Offering New Drug Target

Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

24 Dec 2025

Stem Cell Models Offer Insights Into Early Brain Development and Autism

24 Dec 2025

UT Southwestern Researchers Design Tau Protein to Combat Neurodegenerative Diseases

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies. These findings, reported in Structure, could lead to new treatments for conditions including Alzheimer's disease, frontotemporal dementia, chronic traumatic encephalopathy (CTE), and progressive supranuclear palsy.

24 Dec 2025

Study Challenges Long-Held Assumptions About Mendelian Retinal Disorders

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

23 Dec 2025

New vCATCH Method Maps Drug Binding Across Every Cell in the Body

When you take a drug, where in your body does it actually go? For most medications, scientists can make only educated guesses about the answer to this question.

23 Dec 2025

Protein MCL1 Emerges as a Central Regulator of Cancer Metabolism

The researchers have succeeded in tracing two classic hallmarks of cancer – the evasion of apoptosis (a form of programmed cell death) and the dysregulation of energy metabolism – back to a common molecular mechanism.

23 Dec 2025

Wasatch Biolabs Announces Co-Marketing Agreement with Agilent to Advance Native-Read Targeted Sequencing

Wasatch BioLabs (WBL), a leader in native, long-read sequencing and epigenomic analysis, today announced a co-marketing agreement with Agilent Technologies to support the adoption of its Direct Targeted Methylation Sequencing (dTMS) platform.

22 Dec 2025

Researchers Map Gene Activation in Lethal Fungal Outbreaks

Scientists have discovered a genetic process which could unlock new ways to treat mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.

22 Dec 2025

Study Identifies Protein Target to Overcome Drug Resistance in NSCLC

Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States.

22 Dec 2025

A Global Catalog of Human Pluripotent Stem Cell Lines for Clinical Use

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental pipelines.

19 Dec 2025

Genetic Differences Can Undermine Antibody-Based Therapies

The genome differs from person to person in thousands of positions. In some cases, this means that proteins have a different building block in certain regions, rendering some antibody-based therapies ineffective, report researchers from the University of Basel, Switzerland.

18 Dec 2025

Smart Hydrogel Senses Infected Wounds and Delivers the Right Treatment

The novel hydrogel adapts to wound environments, offering precise antibacterial and regenerative support, addressing the challenges of infected wounds.

18 Dec 2025

SIGLEC12 Identified as Key Driver Of Necroptosis in Humans

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis.

12 Dec 2025

Visualizing How Cancer Seed Cells Evade Brain Immunity

Metastasis occurs when cancer cells break away from the original tumor and travel through the bloodstream to form new tumors in other parts of the body. It is the leading cause of cancer-related death. Brain metastasis is particularly severe and affects 10-30% of patients with advanced lung, breast, and melanoma cancers.

12 Dec 2025