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Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

10 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Although DNA repair is one of the fundamental processes required for normal human embryonic development, little has been known about how it operates during the earliest stages of development.

10 Sep 2026

Computational Chemistry Breakthrough Yields Targeted Molecule for Acute Myeloid Leukemia Treatment

Pushing the accelerator and the brake at the same time is rarely a good idea. But researchers at the University of Gothenburg are using this approach to treat leukemia.

9 Sep 2026

How Can Stressed Mitochondria Actually Protect Your Heart?

Mitochondria are popularly known as the “powerhouse of the cell,” but these cellular structures do so much more–including acting as signaling hubs.

9 Sep 2026

UCLA Breakthrough Generates Thousands of Allogeneic T-Cell Doses From Single Cord Blood Sample

T cell receptor, or TCR, therapy is a cancer treatment that genetically reprograms immune cells, called T cells, to hunt down cancer with precision.

9 Sep 2026

Loss of Matrix Receptors Impairs Actin Cytoskeleton Remodeling, Cell Spreading, and Osteogenic Differentiation

During bone healing, skeletal progenitor cells (SPCs), which can multiply and develop into bone-forming cells, move to the injury site and help build new bone.

9 Sep 2026

New Platform Promises Rapid Vaccine Monitoring and Biomarker Discovery for Emerging Pathogens

A research team comprising Associate Professor FUNAKOSHI Yohei, Associate Professor YAKUSHIJIN Kimikazu, Professor MINAMI Hironobu, and Associate Professor OHJI Goh of Kobe University, together with graduate student MASUDA Genki, then-graduate student IIZUMI Shunsuke, Associate Professor OHUE Masahito, and colleagues at the Institute of Science Tokyo, has developed a new analysis method, LM-QASAS.

9 Sep 2026

Advanced RNA Sequencing Separates Rare Regenerative Cells From Mature Tissue

Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the unspecialized stem cells that give rise to the body's tendons and ligaments, the tissues connecting muscles and bones.

8 Sep 2026

Salk Study Uncovers How Mitochondrial Signals Drive Lasting Cardioprotection

Mitochondria are popularly known as the "powerhouse of the cell," but these cellular structures do so much more-including acting as signaling hubs.

7 Sep 2026

Macrophages Function as Trash Collectors for Energy-Demanding Tissues

The body's heart muscle (for pumping blood), skeletal muscle (for movement and posture), and brown fat (for heat production), each require a lot of energy and make a lot of waste. And that waste needs to be managed.

7 Sep 2026

Scientists Build a Genetic Score for Alzheimer’s Disease that Works Across Ancestries

Researchers developed a multi-ancestry genetic risk score for Alzheimer's, correlating genetic factors with cognitive performance and brain health markers.

7 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

A Rutgers-led international team co-authored a study, which was published in Nature Neuroscience, revealing 36 genes significantly increasing the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders. This research offers the most comprehensive biological insight into the development of these conditions and potential future treatments.

4 Sep 2026

Genetic Prediction Tools May Misjudge Mutation Risks, Study Finds

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

4 Sep 2026

OGT Expands Sureseq™ Universal NGS Unique Dual Index (UDI) Capabilities to Support Upto 384 Samples Per Sequencing Run

OGT, a leading global provider of genomic research and diagnostic solutions, today announced the expansion of its SureSeq™ Universal NGS Unique Dual Index (UDI) range, enabling laboratories to multiplex up to 384 uniquely indexed samples in a single sequencing run.

4 Sep 2026

Bacterial Chemical Signals Work Together to Control Intestinal Movement

Mayo Clinic researchers have discovered that chemical signals produced by gut bacteria work together to control intestinal movement.

3 Sep 2026

Study Reveals Hidden Mutational Process in Colorectal Cancer

The discovery of SBS111 in colorectal cancer offers new perspectives on mutational processes and DNA repair, emphasizing its significance in tumor biology.

3 Sep 2026

Optical Metabolic Imaging Profiles Single-Cell Metabolic Fitness in Blood Without Dye Labeling

A routine blood sample contains a diverse collection of immune cells that can reveal important clues about health and disease. These cells, known as peripheral blood mononuclear cells (PBMCs), are widely used to study infections, autoimmune disorders, cancer, and the immune system's response to treatment.

3 Sep 2026

UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and co-leader of the Cancer Cell Biology Research Program at UNC Lineberger Comprehensive Cancer Center, has been awarded a prestigious $700,000 grant from the Mathers Foundation to support research into the role of the endoplasmic reticulum in T-cell metabolism and cancer development.

2 Sep 2026

Clinical News and Research

Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Computational Chemistry Breakthrough Yields Targeted Molecule for Acute Myeloid Leukemia Treatment

How Can Stressed Mitochondria Actually Protect Your Heart?

UCLA Breakthrough Generates Thousands of Allogeneic T-Cell Doses From Single Cord Blood Sample

Loss of Matrix Receptors Impairs Actin Cytoskeleton Remodeling, Cell Spreading, and Osteogenic Differentiation

New Platform Promises Rapid Vaccine Monitoring and Biomarker Discovery for Emerging Pathogens

Advanced RNA Sequencing Separates Rare Regenerative Cells From Mature Tissue

Salk Study Uncovers How Mitochondrial Signals Drive Lasting Cardioprotection

Macrophages Function as Trash Collectors for Energy-Demanding Tissues

Scientists Build a Genetic Score for Alzheimer’s Disease that Works Across Ancestries

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

Genetic Prediction Tools May Misjudge Mutation Risks, Study Finds

OGT Expands Sureseq™ Universal NGS Unique Dual Index (UDI) Capabilities to Support Upto 384 Samples Per Sequencing Run

Bacterial Chemical Signals Work Together to Control Intestinal Movement

Study Reveals Hidden Mutational Process in Colorectal Cancer

Optical Metabolic Imaging Profiles Single-Cell Metabolic Fitness in Blood Without Dye Labeling

UNC Researcher Wins Mathers Foundation Grant to Study T-Cell Metabolism

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