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Invasive E. coli Strains Promote Host Invasion of Harmless Strains

When scientists assess how dangerous a bacterium is, the first question often seems simple: can it be stopped or killed?

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Personalized Support Boosts Genetic Testing Uptake Among At-Risk Family Members

Among cancer patients who received personalized support and navigation services from experts throughout the genetic testing process, their first-degree relatives – parents, siblings and children – were significantly more likely to receive genetic testing, as well. Nearly half of those relatives carried a BRCA1 or BRCA2 mutation, which are associated with a higher risk of cancer, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

30 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

29 Sep 2026

Study Links OCA2 Gene Mutations to Non-Melanin Ocular Developmental Defects

Tiny, striped zebrafish are helping scientists trace how a gene linked to albinism influences eye development, work that may ultimately help explain some of the vision problems experienced by people with the condition and guide the search for new treatments.

29 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

AI Decodes Spatial DNA Packaging Patterns Invisible to Researchers

Aging progressively affects the functioning of our body and, among other things, deteriorates the ability of the hematopoietic system- the set of organs and tissues responsible for producing blood cells- to maintain adequate blood cell production.

28 Sep 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Neutrophil Activation by NMU Blocks Cytotoxic T Cell Tumor Infiltration

A new study from The Wistar Institute has found a link between the nervous system and the rapid development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

26 Sep 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Type I Interferon Pathway Identified as Crucial Innate Viral Defense

Tick populations are expanding across the U.S., driving an increase in tick-borne diseases. Among them is Powassan virus, a rare but increasingly reported infection that can cause severe brain inflammation and lasting neurological complications.

25 Sep 2026

Ultra-High-Resolution 3D Microscopy Captures Distinct Presynaptic Protein Organization States

A new study led by researchers at the University of Wisconsin School of Medicine and Public Health examines how different versions of the same protein can alter neuronal communication.

25 Sep 2026

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

A world-first test developed by researchers at the Garvan Institute of Medical Research has identified the genetic cause of inherited muscle disease in people who remained without answers after years, sometimes decades, of standard testing.

25 Sep 2026

Marine Carbohydrate Therapeutics: From Structural Diversity to Clinical Translation

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

24 Sep 2026

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

24 Sep 2026