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PARP1 Disassembles Nucleosomes to Facilitate Essential DNA Damage Repair

When DNA is damaged, cellular processes respond and repair the DNA. Inhibiting DNA damage repair can be therapeutically beneficial in cancers with genetic vulnerabilities related to DNA damage response.

26 Oct 2026

Taurine Deficiency Triggers Innate Immune Sensing of Cellular Danger Signals

Sustained low-level inflammation is a hallmark of the aging process. The accumulating damage persistently activates the innate immune system-the body's first line of defense-leading to what is known as inflammaging, functional decline and chronic diseases of old age.

26 Oct 2026

Massive Genetic Study Explores How Thousands of Variants Shape Personality

A massive genetic study offers one of the clearest pictures yet of how DNA contributes to personality, identifying genetic variants associated with five major personality traits.

24 Oct 2026

New RNA Extraction Approaches Overcome Agarose Barriers in Lung Slices

Precision-cut lung slices allow researchers to study living human lung tissue outside the body, preserving the different cell types and structures that make up the organ.

24 Oct 2026

Long-Read Nanopore Sequencing Resolves Unexplained Tumor Mutations

Michigan's Oncology Sequencing Program, or MiOncoSeq, was the first of its kind in the nation to sequence patient tumors.

24 Oct 2026

New Genetic Map Identifies Variations Linked to Long QT Syndrome

Using an innovative, high-throughput technique, an international collaboration led by Vanderbilt Health researchers has created a "map" of 1,757 genetic variations that can trigger a life-threatening heart rhythm disorder called long QT syndrome.

24 Oct 2026

Scientists Discover Molecular Cascade Behind Brain Dysregulation in Angelman Syndrome

Angelman syndrome is a rare disease with a single known cause: one missing gene. The lack of that gene, normally inherited from the mother, occurs in approximately one in 20,000 births and is associated with cognitive and mobility deficits that become evident in children when they are around 6 months of age.

24 Oct 2026

BioUK Awards 2026 Celebrate Outstanding Achievement and Breakthrough Innovations from Across the Life Sciences

BioUK, the not-for-profit membership organization focused on catalyzing success in UK life sciences, today announced the winners of the 18th annual BioUK Awards following a ceremony hosted at the Royal Lancaster Hotel, London.

From BioUK 23 Oct 2026

Promega UK Launches Lumit® Insulin Immunoassay

A new homogeneous, wash-free, plate-based assay that enables researchers to rapidly measure insulin secretion using a simple add-and-read format, delivering robust results ideal for metabolic disease drug discovery.

From Promega Corporation 22 Oct 2026

BioNTech Opens mRNA Manufacturing Facility at La Trobe

La Trobe University is now home to one of the world’s leading biopharmaceutical companies, with the official opening of BioNTech’s state-of-the-art, clinical-scale mRNA manufacturing and research facility at the University’s campus in Melbourne’s north.

From BioNTech SE 22 Oct 2026

Millions of Older Australians Exposed to Overlapping Medication Risks

An estimated 2.3 million older Australians are being dispensed multiple medicines associated with falls and fractures, while more than 1.2 million are receiving combinations linked to kidney-related side effects, according to new research from Adelaide University.

20 Oct 2026

Study Details Genetic Divergence Between Astrocytomas and Oligodendrogliomas

Treatment-resistant brain cancers develop different mutations as they become more aggressive, according to new research from Yale School of Medicine.

20 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Live Organelle Imaging Catches Early Neuronal Stress Before Cell Death

Scientists studying amyotrophic lateral sclerosis (ALS), Parkinson's, Alzheimer's and other neurological diseases are getting unprecedented views inside brain cells, using powerful new microscopes to uncover changes that may begin long before neurons die.

20 Oct 2026

Cedars-Sinai Expands Stem Cell Research Aboard the Space Station

When NASA’s SpaceX CRS-35 mission docks with the International Space Station Oct. 15, it will deliver two experiments from the Cedars-Sinai Center for Space Medicine Research.

16 Oct 2026

Balancing Immune Cells May Unlock Hidden Human Regenerative Potential

In a study of fingertip regeneration, a team led by JAX Senior Research Scientist James Godwin found that some immune cells in mice can attack and kill cells needed to rebuild bone, while a subset of those same immune cells can protect the bone-making cells and allow regeneration to continue.

16 Oct 2026

Novel Molecular Pathway Identified to Combat T-Cell Exhaustion in Cancer

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center used a CRISPR screen to identify a key molecular pathway that drives exhaustion in cancer-fighting immune cells, limiting their ability to keep tumors under control.

16 Oct 2026

AI Partnership Aims to Personalize IVF Treatment, Improve Patient Outcomes

La Trobe University and reproductive health innovator GonGlobal have entered into a strategic collaboration to develop and validate advanced artificial intelligence (AI) and digital twin technologies for Assisted Reproductive Technology (ART) and In Vitro Fertilization (IVF).

16 Oct 2026

Could mRNA Vaccine Technology Help Repair Damaged Livers?

Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery.

16 Oct 2026