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Constructing Large-Scale Pangenomes Using a Cost-Effective Hybrid Sequencing Strategy

A research team led by Zhen-Xing Endowed Professor Jian Yang at the School of Life Sciences, Westlake University, together with collaborators, published their latest findings in Nature on April 1. The study innovatively developed a pangenome-informed genome assembly (PIGA) method.

6 Apr 2026

New Tool Directly Transfers Cytoplasm and Organelles Between Living Cells

Cells are not isolated units; they continuously exchange proteins, genetic material, and even entire organelles with their neighbors.

6 Apr 2026

Researchers Discover Prenatal Genetic Origins of Childhood Absence Epilepsy

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to epilepsy and related cognitive challenges.

6 Apr 2026

How Bacterial Enzymes Use Ratchet Mechanisms to Break Down Collagen

Collagen is an important protein that helps build the tissues of humans and animals. It is very strong because it is made of three protein strands twisted tightly together like a rope. Because of this sturdy structure, ordinary protein-cutting enzymes usually cannot break it down.

6 Apr 2026

Study Highlights Unexpected Role of Stard7 in Colorectal Cancer Development

A new study led by researchers at the University of Liège highlights the unexpected role of Stard7 in the development of intestinal cancers.

3 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Molecular Switch AHR Limits Neuron Regeneration and Axon Repair

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

3 Apr 2026

Defining Tumor Microbiota for Improved Cancer Diagnosis and Treatment

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

3 Apr 2026

Regenerative Vascular Grafts Solve Key Shortage In Surgery

Engineered biotubes demonstrate strong mechanical performance and rapid tissue regeneration, offering a scalable solution to the vascular graft shortage.

2 Apr 2026

New Gene-Editing Approach Eliminates Painful Crises in Sickle Cell Disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

2 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Researchers Use Retron Systems to License DNA for Cellular Tasks

Stepping away from its billions-of-years-old role as a genetic "blueprint," DNA is now embarking on a new journey as an active "field agent" within cells. This research by a team led by Professor Jongmin Kim and Ph.D. candidate Geonhu Lee from the Department of Life Sciences at POSTECH (Pohang University of Science and Technology) was published in the online edition of the international chemistry journal, Nature Chemistry.

2 Apr 2026

New Framework Prioritizes Uncertain Genetic Variants in Cancer Profiling

Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling (CGP) of cancers.

1 Apr 2026

Nonviral Nanoparticles Show Promise for Safer Gene Delivery Methods

In a demonstration that helps pave the way for gene therapies with fewer side effects, several human cell types were genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine.

1 Apr 2026

Study Reveals Hidden Diversity in Rising Strep Bacterium

Scientists at Houston Methodist Research Institute have discovered that a fast‑rising strep bacterium comes in more forms than expected, including ones that may lead to life-threatening infections.

1 Apr 2026

How To Create Long-Lasting Immune Cells For Stronger Vaccines

Scientists at the University of Wisconsin School of Veterinary Medicine have identified a potential approach to develop longer-lasting vaccines for respiratory viruses such as influenza and the coronavirus that causes COVID-19.

1 Apr 2026

Discovery Challenges the Theory That Proteins Move Mainly by Diffusion

Scientists at Oregon Health & Science University have uncovered a previously unknown system of internal "trade winds" that help cells rapidly move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing.

31 Mar 2026