Medicine News and Research

RSS

Study Identifies Adipogenin as Crucial Driver of Lipid Droplet Formation

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

27 Nov 2025

UBQLN2 Liquid Droplets Found to Catalyze Early α-Synuclein Aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease. α-synuclein (α-syn), a misfolded protein, aggregates and forms fibrils, which leads to the formation of LBs.

27 Nov 2025

Kinase Inhibitors Found to Trigger Widespread Target Protein Degradation

Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins.

27 Nov 2025

Breakthrough Reveals How Immune Cells Orchestrate Pathological Scarring

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

26 Nov 2025

Freezing Cells for Success: DMSO-Free Redefining the Future of Cryopreservation

Cryopreservation plays a crucial role in cell biology research, bioprocessing, and biomanufacturing. Traditionally, DMSO (dimethyl sulfoxide) has been the cryoprotectant of choice for preserving cells.

25 Nov 2025

Old Blood Stem Cells Regain Regenerative Capacity Through Lysosomal Intervention

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

25 Nov 2025

New Technique Reveals Synaptic Vesicle Dynamics in Living Brain Tissue

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Targeting Rhoa to Restore Function in Hematopoietic Stem Cells

Aging is defined as the deterioration of function overtime, and it is one of the main risk factors for numerous chronic diseases.

25 Nov 2025

Novel Mechanism for Epigenetic Patterning in Plants

Every cell within an organism shares an identical genetic blueprint. Their distinct identities stem from epigenetics—precise chemical markers that dictate gene expression.

24 Nov 2025

Senescent Blood Vessel Cells Drive the Development of Metabolic Disorders

Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes.

24 Nov 2025

Optogenetic Tool Uncovers Key Role of Mechanical Forces in Early Embryonic Development

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

24 Nov 2025

New Tool Maps Microbial Activity to Transform Gut Health Research

The gut microbiome is made up of trillions of microbes that play a vital role in keeping us healthy.  A disturbance in the balance of these microbes can contribute to a variety of health conditions, such as inflammatory bowel disease (IBD).

22 Nov 2025

New Polygenic Risk Scores Transform Disease Prediction for Han Chinese Populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

22 Nov 2025