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Study Redefines Structural Framework of Primate Cone Photoreceptor Outer Segments

For over 60 years, scientists have debated a basic structural question about cone photoreceptors, the cells that let vertebrates see color: are their light-sensing disk membranes closed off inside the cell, or are they open to the extracellular space?

12 Sep 2026

Study Uncovers Hidden Human "Dark Proteome" Members Across Protein Models

Hundreds of millions of proteins make up the known protein universe, but most remain largely unexplored. Inside the human body, thousands of these dark proteins remain mysteries. Scientists may know they exist, but not what they do or why they matter.

12 Sep 2026

Researchers Locate Cortical Cells That Actively Trigger Brain Sleep

What makes the brain fall asleep? For nearly a century, scientists have looked to structures deep within the brain for the answer.

12 Sep 2026

Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

Two enduring biological mysteries have remained unsolved for decades: why almost everyone who loses weight gains it back, no matter how they lost it, and why obesity passes from mother to child at rates that diet and environment cannot explain. Now, scientists from Harrington Discovery Institute at University Hospitals and Case Western Reserve University have identified why.

11 Sep 2026

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous. Previously, the identity of these surviving cells was unclear.

11 Sep 2026

Reprogramming Tumor Immune Microenvironment to Combat Aggressive Glioblastoma Brain Cancer

Mayo Clinic researchers have identified a potential new approach to treating glioblastoma that could help the immune system fight the aggressive brain cancer while improving the effectiveness of existing chemotherapy.

11 Sep 2026

Researchers Decode High-Pressure Survival Strategy of Deep-Sea Bacteria

Life in the deep sea is under immense pressure—literally. Such extreme conditions can disrupt the delicate structures of proteins essential to life. Yet somehow, the proteins in deep-sea creatures remain functional. This raises an intriguing question: how?

11 Sep 2026

Molecular Circuit Linking Abscisic Acid Signaling to Tanshinone Production Uncovered

Salvia miltiorrhiza, also known as Danshen, is a highly regarded traditional Chinese medicine widely used for treating cardiovascular and cerebrovascular diseases. Its medicinal properties are largely attributed to tanshinones-a group of more than 40 diterpenoid quinone compounds, including tanshinone I, tanshinone IIA, and cryptotanshinone, which predominantly accumulate in the plant's roots.

11 Sep 2026

Hidden Immune Cells May Hold Key to Tackling Female Infertility

University of Manchester scientists have uncovered a hidden role for immune cells in the womb, opening the door to new treatments for infertility, miscarriage and other reproductive conditions that affect millions of women worldwide.

10 Sep 2026

Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

10 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

Researchers Discover Groundbreaking Protein-Stabilizing Antiviral for Ebola

A University of Minnesota-led multi-institutional research team has discovered a highly potent small molecule that blocks Ebola virus entry by stabilizing the virus's entry protein and provides strong protection when given orally in a preclinical model.

10 Sep 2026