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Researchers Decipher the Rules Behind Cellular Quality Control In Humans

A research team at the University of Cologne and the Max Delbrück Center in Berlin has deciphered in detail the rules behind an important mechanism of cellular quality control in humans.

13 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

Adaptive Microfluidic Channel Enhances Impedance Flow Cytometry Sensitivity

Many advances in medicine and drug development were possible owing to flow cytometry, a single-cell analysis technique that analyzes cells using the emitted fluorescence of their chemical tags while passing through a laser beam.

13 Sep 2025

New Research Shows How Genes Shape Gut Bacteria

Maintaining the abundance and happiness of the good bacteria in our stomachs is a profitable endeavor supported by supplements and fad diets that promise to be the secret to gut health.

12 Sep 2025

Metastatic Lung Cancer Cells Cozy Up to Neurons and Form Synapses

Small cell lung cancer cells that metastasize to the brain cozy up to neurons and form working electrical connections, called synapses, according to an upcoming study led by Stanford Medicine researchers.

11 Sep 2025

Genes Actively Work to Shape a Healthy Gut Microbiome

New research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.

11 Sep 2025

PhoBITs Enable Unprecedented Control of Cellular Pathways with Blue Light

Imagine being able to flip a light switch to control disease pathways inside a living cell. A team of visionary researchers at the Texas A&M University Health Science Center (Texas A&M Health) is making this dream a reality with their groundbreaking genetic tools known as photo-inducible binary interaction tools, or PhoBITs.

10 Sep 2025

Tracing Origins of Wnt Signaling Through the Lipocone Superfamily

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key players in human development.

10 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Stress Reshapes Brain Cells and Alters Activity in Mice

Canadian researchers show that stress modifies the morphology of brain cells in mice, directly influencing the rodents' level of physical activity.

5 Sep 2025

Earth BioGenome Project Aims to Build a Digital Library of All Life

From the mighty blue whale to the humble baker’s yeast, scientists have barely begun to understand the vast genetic diversity among lifeforms.

5 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Scientists Uncover Hidden Role of Cas9 in Building Bacterial Immune Memory

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of living cells.

4 Sep 2025

Microbial Signatures Help Distinguish Colorectal Tumors from Other Cancers

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

4 Sep 2025

Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025

DNA-Wrapped Nanoparticles Enhance Efficiency of Gene Editing Tools

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine.

2 Sep 2025

Genetic On-Off Switch for Cilia Formation Uncovered

Some might say it looks like a finger. Others might see a worm. Scientists in the field often liken it to an antenna. The technical name is primary cilium.

2 Sep 2025

Mathematical Approach Restores Altered Cellular Responses to Normal States

Previously, research on controlling gene networks has been carried out based on a single stimulus-response of cells.

2 Sep 2025

Discovery of Dendritic Cell Reprogramming Opens Path to Tailored Cancer Treatments

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

2 Sep 2025