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How Toxic Protein Spreads in Huntington’s Disease

Huntington's disease is a debilitating brain disorder that gradually robs people of mobility, memory, and personality.

23 Mar 2026

Scientists Develop Method to Sequence Proteins Using DNA Technology

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions.

19 Mar 2026

PAX3 Protein Plays Key Roles in Development and Cancer

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression.

19 Mar 2026

Molecular Switch Links Mitochondrial Stress to T Cell Exhaustion

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed.

19 Mar 2026

New Computational Tool Streamlines Analysis of Massive Genomic Datasets

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models or cultured cells.

19 Mar 2026

New Ring Structure Guides Precise Cell Death and Immunity

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms.

16 Mar 2026

Solving a 50-year Bottleneck in Chemotherapy Drug Production

A multinational team of researchers has made a significant advance in the manufacturing of doxorubicin, a crucial chemotherapy drug.

16 Mar 2026

Unexpected SRC Localization Offers Promising Target for Cancer Therapies

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

16 Mar 2026

Certain Antibiotics Leave Lasting Footprints on Human Gut Microbiome

Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time.

13 Mar 2026

Novel INSTALL Technology Achieves Non-Toxic Gene Integration in Multiple Cell Types

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

12 Mar 2026

Study Reveals Microbiome Role in Protecting the Colon From Tissue Injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

11 Mar 2026

Cardiff University Decodes Catastrophic DNA Rearrangement

Cardiff University researchers discovered how a particularly severe type of DNA damage occurs, giving fresh insight into mutation mechanisms that contribute to cancer and inherited genetic diseases.

11 Mar 2026

Genetic Analysis Uncovers Shared Biology Across Major Psychiatric Conditions

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

10 Mar 2026

New AI Tool Guides Chemists Toward Faster Drug Discovery

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine.

10 Mar 2026

Advanced Genome Sequencing Reveals Hidden Genetic Variants Linked to Autism

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads large sections of the genome at once, making it easier for scientists to find new genetic variants and understand how genetic variants affect the function of a gene.

10 Mar 2026

Setd8 Enzyme Preserves Retinal Progenitor Identity During Eye Development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

10 Mar 2026

Optovolution Uses Light to Guide the Evolution of Dynamic Proteins

Evolution is biology's powerful method of engineering. It works by generating many variants of DNA, RNA, and proteins inside cells and letting nature "select" the organism that performs best.

9 Mar 2026

ANKIB1 Identified as the Essential Master Switch for Innate Immunity

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.

9 Mar 2026

Specialized Tanycyte Brain Cells Found to Play Key Role in Tau Clearance

Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer's disease. In a paper publishing March 5 in the Cell Press journal Cell Press Blue, researchers report a previously unknown mechanism that appears to enable the build-up of tau.

6 Mar 2026

Genetically Engineered Stem Cells Successfully Overcome Immune Rejection in Mice

A study published today in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model.

6 Mar 2026