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New Framework Uses Genetic Variant Data to Recall Biobank Participants

Clinical biobanks that combine genomic data with electronic health records (EHRs) have become powerful resources for discovering genetic variants associated with disease.

28 Jul 2026

Dengue Virus Replicates Inside Memory B Cells to Evade Immunity

Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse, NY, have discovered that dengue virus can infect and replicate inside memory B cells, immune cells traditionally understood to help protect the body from infection.

28 Jul 2026

Novel Dendritic Cell Vaccine Redirects Viral Memory to Fight Tumors

In a discovery that could redefine the future of cancer immunotherapy, scientists from Celloram Inc., University Hospitals and Case Western Reserve University have developed a novel cancer vaccine platform that transforms the impact of the largest immunological event in modern history

28 Jul 2026

3D Mapping of Tonsil Genetic Structures Unlocks Antibody Optimization

About 2 meters worth of genetic material must fit into the nucleus of each and every one of most of our trillions of cells, coiling and winding to form what looks like a tangled mess.

28 Jul 2026

Engineered Probiotic Bacteria Deliver Immune Therapy Directly Into Pancreatic Tumors

Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.

27 Jul 2026

Synthetic Biology Breakthrough Rebuilds Basic Features of Cellular Life

Nature is beautiful, powerful and essential. But nature is not always gentle. The same biological world that gives rise to forests, coral reefs and human life also produces infections, cancer, genetic disease, crop blights and toxins.

24 Jul 2026

Scientists Uncover Unexpected Mechanism Behind Extreme Antibiotic Resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

24 Jul 2026

Study Reveals How Genome Regulation Changes During Brain Aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

24 Jul 2026

Scientists Discover Altered 3D Genome Structure in Alzheimer’s Brains

Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington shed new light on Alzheimer's disease that could point to new directions for treatment.

24 Jul 2026

Researchers Find New Bacterial Mechanism for Evading Antibiotic Exposure

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.

24 Jul 2026

Changes in RNA Regulation Enable Bacteria to Enter Antibiotic Tolerance

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics. St. Jude Children's Research Hospital scientists have uncovered how S. pneumoniae adapts to antibiotic exposure and immune pressures.

23 Jul 2026

Artificially Recreating C3 Effects Overcomes Resistance in Hard-to-Treat Tumors

An ancient molecule that existed long before the blood circulation system evolved, has been found to support cancer immunotherapy. Researchers at Nagoya University in Japan found that complement C3 protein acts inside tumors to prevent the accumulation of immunosuppressive cells, but only when produced inside the tumor.

23 Jul 2026

CRISPR Gene Editing Reveals How Enhancer Hierarchies Regulate Gene Expression

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

23 Jul 2026

New Open Source AI Toolkit Identifies Promising Peptide Medicines

Penn Engineers have developed PeptiVerse, an AI-powered platform that predicts key chemical and biological properties of peptides, the strings of amino acids whose medical potential has been demonstrated by the success of GLP-1 drugs, the widely used weight-loss treatments.

22 Jul 2026

Engineered Mice Carrying the Genetic Variant Develop Excessive Sweating

Johns Hopkins Medicine researchers have identified a genetic driver of primary idiopathic hyperhidrosis, a chronic condition that causes excessive sweating, providing some of the strongest evidence to date that the disorder can originate in the nervous system and may be treatable with targeted therapies.

22 Jul 2026

Study Identifies miR-16 as a Robust Marker of Muscle Wasting

Cachexia-a syndrome characterized by progressive muscle wasting-affects both humans and dogs with chronic diseases such as cancer.

22 Jul 2026

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Demographic Biases Threaten the Fairness of Global Single-Cell Human Atlases

The single-cell "atlases" that are increasingly used to map the human body and as training data for artificial intelligence models, may not represent the world's populations fairly, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai.

21 Jul 2026

New Method Derives Red Blood Cell-Like Cells From Canine iPSCs

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

20 Jul 2026

Hospital-Trained AI Outperforms GPT-5 At Reading Brain Scans

An AI model trained on hospital brain scans outperforms leading systems in diagnostics and triage, showcasing the potential of clinical data integration.

20 Jul 2026